| Gene Symbol |
SRSF3
|
| Entrez Gene |
6428
|
| Alt Symbol |
SFRS3, SRp20
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
serine/arginine-rich splicing factor 3
|
| Other Description |
pre-mRNA-splicing factor SRP20|splicing factor, arginine/serine-rich 3|splicing factor, arginine/serine-rich, 20-kD
|
| Swissprots |
P84103 Q5R3K0 B4E241
|
| Accessions |
EAX03898 EAX03899 EAX03900 EAX03901 EAX03902 EAX03903 P84103 AB451229 BAG70043 AB451352 BAG70166 AF107405 AAD44523 AK091927 AK095580 AK304097 BAG65003 AK310317 AK312553 BAG35450 BC000914 AAH00914 BC069018 AAH69018 BM833102 BT007017 AAP35663 D28423 BAA05789 DC398250 L10838 AAA36648 NM_003017 NP_003008 NR_036610
|
| Function |
May be involved in RNA processing in relation with cellular proliferation and/or maturation. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA- binding activity. RNA-binding is semi-sequence specific. {ECO:0000269|PubMed:11336712, ECO:0000269|PubMed:18364396}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:11336712}. Cytoplasm {ECO:0000269|PubMed:11336712}.
|
| Top Pathways |
Spliceosome, Herpes simplex infection
|
![Western Blot: SFRS3 Overexpression Lysate (Adult Normal) [NBL1-15889] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SFRS3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/19021_SFRS3%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-15889-img0002.jpg)