Gene Symbol | SRSF3 |
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Entrez Gene | 6428 |
Alt Symbol | SFRS3, SRp20 |
Species | Human |
Gene Type | protein-coding |
Description | serine/arginine-rich splicing factor 3 |
Other Description | pre-mRNA-splicing factor SRP20|splicing factor, arginine/serine-rich 3|splicing factor, arginine/serine-rich, 20-kD |
Swissprots | P84103 Q5R3K0 B4E241 |
Accessions | EAX03898 EAX03899 EAX03900 EAX03901 EAX03902 EAX03903 P84103 AB451229 BAG70043 AB451352 BAG70166 AF107405 AAD44523 AK091927 AK095580 AK304097 BAG65003 AK310317 AK312553 BAG35450 BC000914 AAH00914 BC069018 AAH69018 BM833102 BT007017 AAP35663 D28423 BAA05789 DC398250 L10838 AAA36648 NM_003017 NP_003008 NR_036610 |
Function | May be involved in RNA processing in relation with cellular proliferation and/or maturation. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA- binding activity. RNA-binding is semi-sequence specific. {ECO:0000269|PubMed:11336712, ECO:0000269|PubMed:18364396}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11336712}. Cytoplasm {ECO:0000269|PubMed:11336712}. |
Top Pathways | Spliceosome, Herpes simplex infection |
Human SFRS3 full length protein - ab114674 from Abcam
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Human SFRS3 protein fragment - ab114675 from Abcam
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SRSF3 / SRP20 Antibody Blocking Peptide - LS-E4043 from LifeSpan Bioscience
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SRSF3 / SRP20 Antibody Blocking Peptide - LS-E14750 from LifeSpan Bioscience
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Recombinant Human SFRS3 Protein - H00006428-Q01 from Novus Biologicals
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Recombinant Human SFRS3 Protein - H00006428-P01 from Novus Biologicals
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SFRS3-Antibody-Center-Blocking-Peptide - BP16268c from Abgent, a WuXi AppTec company
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SFRS3 Blocking Peptide - 33R-8935 from Fitzgerald
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SRSF3 Blocking Peptide - abx063252 from Abbexa
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SFRS3 - H00006428-P01-10 from Acris Antibodies
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SFRS3 - H00006428-P01-25 from Acris Antibodies
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SFRS3 - H00006428-Q01-10 from Acris Antibodies
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SFRS3 - H00006428-Q01-25 from Acris Antibodies
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SRSF3 Peptide - 8179P from ProSci
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SRp20 fusion protein - ag13184 from Proteintech Group
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SRp20 fusion protein - Ag1341 from Proteintech Group
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Recombinant Human SRSF3 - SRSF3-26854TH from Creative Biomart
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Recombinant Human SRSF3 - SRSF3-26855TH from Creative Biomart
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SRSF3 Blocking Peptide - CBP2058 from Cohesion Biosciences
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SRp20 (F151) Peptide - BS2559P from Bioworld Technology
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Recombinant Human Serine/arginine-rich splicing factor 3(SRSF3) - CSB-YP021155HU CSB-EP021155HU CSB-BP021155HU CSB-MP021155HU from Cusabio
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Splicing Factor, Arginine/Serine-Rich 3, Peptide - MBS657959 from MyBioSource
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Splicing Factor, Arginine/Serine-Rich 3, Peptide - MBS633814 from MyBioSource
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SFRS3 Protein - NBP2-38815PEP from Novus Biologicals
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SRSF3 Peptide, Human - M34GP15181H from Creative Peptides
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