| Gene Symbol |
ITGB8
|
| Entrez Gene |
3696
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
integrin, beta 8
|
| Other Description |
integrin beta-8
|
| Swissprots |
A4D133 P26012 B4DHD4
|
| Accessions |
AAQ96845 AAQ96846 EAL24275 EAW93724 EAW93725 P26012 AB209429 BAD92666 AK295044 BAG58095 AW516961 BC002630 AAH02630 BC038209 BC042028 BI861225 BT006739 AAP35385 M73780 AAA36034 XM_011515392 XP_011513694 XM_011515393 XP_011513695 XM_011515394 XP_011513696 XM_011515395 XP_011513697 XM_011515396 XP_011513698 NM_002214 NP_002205
|
| Function |
Integrin alpha-V/beta-8 is a receptor for fibronectin.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Tissue Specificity |
Placenta, kidney, brain, ovary, uterus and in several transformed cells. Transiently expressed in 293 human embryonic kidney cells.
|
| Top Pathways |
Focal adhesion, ECM-receptor interaction, Cell adhesion molecules (CAMs), Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC)
|
