Gene Symbol | ITGB8 |
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Entrez Gene | 3696 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | integrin, beta 8 |
Other Description | integrin beta-8 |
Swissprots | A4D133 P26012 B4DHD4 |
Accessions | AAQ96845 AAQ96846 EAL24275 EAW93724 EAW93725 P26012 AB209429 BAD92666 AK295044 BAG58095 AW516961 BC002630 AAH02630 BC038209 BC042028 BI861225 BT006739 AAP35385 M73780 AAA36034 XM_011515392 XP_011513694 XM_011515393 XP_011513695 XM_011515394 XP_011513696 XM_011515395 XP_011513697 XM_011515396 XP_011513698 NM_002214 NP_002205 |
Function | Integrin alpha-V/beta-8 is a receptor for fibronectin. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Placenta, kidney, brain, ovary, uterus and in several transformed cells. Transiently expressed in 293 human embryonic kidney cells. |
Top Pathways | Focal adhesion, ECM-receptor interaction, Cell adhesion molecules (CAMs), Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
Integrin β8 CRISPR/Cas9 KO Plasmid (h) - sc-401379 from Santa Cruz Biotechnology
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Integrin β8 HDR Plasmid (h) - sc-401379-HDR from Santa Cruz Biotechnology
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Integrin β8 Double Nickase Plasmid (h) - sc-401379-NIC from Santa Cruz Biotechnology
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Integrin β8 Double Nickase Plasmid (h2) - sc-401379-NIC-2 from Santa Cruz Biotechnology
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Integrin β8 CRISPR Activation Plasmid (h) - sc-401379-ACT from Santa Cruz Biotechnology
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Integrin β8 CRISPR Activation Plasmid (h2) - sc-401379-ACT-2 from Santa Cruz Biotechnology
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Integrin β8 Lentiviral Activation Particles (h) - sc-401379-LAC from Santa Cruz Biotechnology
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Integrin β8 Lentiviral Activation Particles (h2) - sc-401379-LAC-2 from Santa Cruz Biotechnology
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Integrin β8 siRNA (h) - sc-43137 from Santa Cruz Biotechnology
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Integrin β8 shRNA Plasmid (h) - sc-43137-SH from Santa Cruz Biotechnology
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Integrin β8 shRNA (h) Lentiviral Particles - sc-43137-V from Santa Cruz Biotechnology
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Integrin beta 8 RNAi - H00003696-R02 from Novus Biologicals
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MISSION® esiRNA - EHU014221 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10821 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10821 from Sigma-Aldrich
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ITGB8 siRNA (Human) - CRH2485 from Cohesion Biosciences
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ITGB8 - MBS8210379 from MyBioSource
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shRNA set against Human ITGB8 (NM_002214.2) - SHH321473 from Creative biogene
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shRNA set against Human ITGB8(NM_002214.2) - SHL183996 from Creative biogene
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Human Integrin beta 8 siRNA - orb262987 from Biorbyt
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ITGB8 shRNA Plasmid (Human) - CHH2485 from Cohesion Biosciences
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ITGB8 miRNA 3'UTR clone - MiUTR1H-05041 from Creative biogene
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