UBXN1

Gene Symbol	UBXN1
Entrez Gene	51035
Alt Symbol	2B28, SAKS1, UBXD10
Species	Human
Gene Type	protein-coding
Description	UBX domain protein 1
Other Description	SAPK substrate protein 1|UBA/UBX 33.3 kDa protein|UBX domain-containing protein 1
Swissprots	Q9BV93 Q9BVV5 Q04323
Accessions	CAF06446 CAF06447 CAH05541 CAH05542 EAW74061 EAW74062 EAW74063 EAW74064 EAW74065 EAW74066 EAW74067 Q04323 AI498746 AK054832 BAG51430 AK297856 BAG60188 AK300542 BAG62250 AK303471 BAG64510 AK316012 BAH14383 BC000902 AAH00902 BC001372 AAH01372 BC032689 AAH32689 BC040129 AAH40129 BI855821 BP329601 GQ129328 ACT64462 HQ448734 ADQ33212 M68864 AAA36396 XM_005274033 XP_005274090 XM_011545090 XP_011543392 NM_001286077 NP_001273006 NM_001286078 NP_001273007 NM_015853 NP_056937
Function	Ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.
Subcellular Location	Cytoplasm {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human LOC51035 full length protein - ab162400 from Abcam Category Protein Source Wheat germ Species Human

UBXN1 Antibody Blocking Peptide - LS-E20658 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human UBXN1 Protein - H00051035-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

UBXN1 / SAKS1 - H00051035-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

UBXN1 / SAKS1 - H00051035-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

UBXN1 fusion protein - Ag9146 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human UBXN1, GST-tagged - UBXN1-3565H from Creative Biomart Category Protein Source E.coli Species Human

UBXN1 / SAKS1 - TP300703 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

UBXN1 Protein - NBP1-89387PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

UBXN1-Blocking-Peptide-Center - BP5360c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

UBXN1 Peptide, Human - M34GP17012H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Human UBXN1 Protein, GST-tagged - UBXN1-4776H from Creative Biomart Category Protein Source Wheat Germ Species Human

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