Gene Symbol | EPHA6 |
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Entrez Gene | 285220 |
Alt Symbol | EHK-2, EHK2, EK12, EPA6, HEK12, PRO57066 |
Species | Human |
Gene Type | protein-coding |
Description | EPH receptor A6 |
Other Description | EPH homology kinase 2|EPH-like kinase 12|ephrin receptor EphA6|ephrin type-A receptor 6 |
Swissprots | Q9UF33 D6RAL5 |
Accessions | CBH19275 EAW79885 Q9UF33 AK092565 BAG52574 AK302040 BAG63434 AK302080 BAG63468 AK310249 AL133666 CAB63775 AY358738 AAQ89098 BC031881 BC067287 BC156733 AAI56734 BX099374 DA385338 DC398430 DN991634 DR731365 DV080244 XM_006713592 XP_006713655 XM_011512705 XP_011511007 XM_011512706 XP_011511008 XM_011512707 XP_011511009 XR_924126 XR_924127 NM_001080448 NP_001073917 NM_001278300 NP_001265229 NM_001278301 NP_001265230 NM_173655 NP_775926 |
Function | Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
Tissue Specificity | Expressed in brain and testis. {ECO:0000269|PubMed:14726470}. |
Top Pathways | Axon guidance |
EphA6 (T-17) - sc-323812 from Santa Cruz Biotechnology
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EphA6 (K-15) - sc-323813 from Santa Cruz Biotechnology
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Anti-Eph receptor A6 antibody - ab113239 from Abcam
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Anti-Eph receptor A6 antibody - ab173390 from Abcam
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Anti-Eph receptor A6 antibody - ab80207 from Abcam
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Anti-Eph receptor A6 antibody - ab58022 from Abcam
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Anti-Eph receptor A6 antibody - C-terminal - ab135807 from Abcam
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Anti-EPHA6 / EPH Receptor A6 Antibody (aa613-712, clone 10C99, Azide-free) - LS-C183599 from LifeSpan Bioscience
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Anti-EPHA6 / EPH Receptor A6 Antibody (Extracellular Domain) - LS-C125531 from LifeSpan Bioscience
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Anti-EPHA6 / EPH Receptor A6 Antibody (aa665-680) - LS-C147868 from LifeSpan Bioscience
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Anti-EPHA6 / EPH Receptor A6 Antibody (C-Terminus, Biotin) - LS-C219015 from LifeSpan Bioscience
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Anti-EPHA6 / EPH Receptor A6 Antibody (C-Terminus, APC) - LS-C219014 from LifeSpan Bioscience
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Anti-EPHA6 / EPH Receptor A6 Antibody (C-Terminus, AP) - LS-C219013 from LifeSpan Bioscience
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Anti-EPHA6 / EPH Receptor A6 Antibody (C-Terminus, FITC) - LS-C219016 from LifeSpan Bioscience
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Anti-EPHA6 / EPH Receptor A6 Antibody (C-Terminus, Azide-free, HRP) - LS-C219017 from LifeSpan Bioscience
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Anti-EPHA6 / EPH Receptor A6 Antibody (clone 3D5B10) - LS-C109092 from LifeSpan Bioscience
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Anti-EPHA6 / EPH Receptor A6 Antibody (aa613-712) - LS-C307403 from LifeSpan Bioscience
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Anti-EPHA6 / EPH Receptor A6 Antibody (C-Terminus, PE) - LS-C219018 from LifeSpan Bioscience
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Anti-EPHA6 / EPH Receptor A6 Antibody (C-Terminus) - LS-C330426 from LifeSpan Bioscience
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Anti-EPHA6 / EPH Receptor A6 Antibody (aa313-362) - LS-C169763 from LifeSpan Bioscience
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Anti-EPHA6 / EPH Receptor A6 Antibody - LS-C100267 from LifeSpan Bioscience
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Anti-EPHA6 / EPH Receptor A6 Antibody (aa1006-1035) - LS-C100266 from LifeSpan Bioscience
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Anti-EPHA6 / EPH Receptor A6 Antibody (aa891-940) IHC-plus⢠- LS-B4905 from LifeSpan Bioscience
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Anti-EPHA6 / EPH Receptor A6 Antibody (aa930-961) - LS-C344657 from LifeSpan Bioscience
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Anti-EPHA6 / EPH Receptor A6 Antibody (aa665-680) - LS-C36248 from LifeSpan Bioscience
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