MGARP
| Gene Symbol | MGARP |
|---|---|
| Entrez Gene | 84709 |
| Alt Symbol | C4orf49, CESP-1, HUMMR, OSAP |
| Species | Human |
| Gene Type | protein-coding |
| Description | mitochondria-localized glutamic acid-rich protein |
| Other Description | corneal endothelium-specific protein 1|hypoxia up-regulated mitochondrial movement regulator protein|ovary-specific acidic protein|protein MGARP |
| Swissprots | Q8TDB4 Q9BZC3 |
| Accessions | EAX05122 Q8TDB4 AF329088 AAG59896 AF484960 AAM09685 BC037987 BC104173 AAI04174 BC104174 AAI04175 NM_032623 NP_116012 |
| Function | Plays a role in the trafficking of mitochondria along microtubules. Regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. Participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion. Also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology (By similarity). {ECO:0000250}. |
| Subcellular Location | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Mitochondrion {ECO:0000269|PubMed:16565373, ECO:0000269|PubMed:21447634}. Mitochondrion outer membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Colocalizes with RHOT1, RHOT2, TRAK1 and TRAK2 at the mitochondrion. {ECO:0000250}. |
| Tissue Specificity | Expressed in the brain, adrenal gland and corneal endothelium (CE). Expressed in steroid-producing cells of the ovary and testis (at protein level). Expressed in steroid- producing cells of the ovary and testis. Weakly expressed in placenta. Expressed in corneal endothelial cells. {ECO:0000269|PubMed:12036975, ECO:0000269|PubMed:12770732, ECO:0000269|PubMed:16565373, ECO:0000269|PubMed:19325000, ECO:0000269|PubMed:19528298}. |
OSAP (T-16) - sc-243691 from Santa Cruz Biotechnology
|
||||||||||
Anti-Ovary-specific acidic protein antibody - ab106286 from Abcam
|
||||||||||
Anti-Ovary-specific acidic protein antibody - ab123577 from Abcam
|
||||||||||
Anti-C4orf49 / OSAP Antibody (N-Terminus) - LS-C144803 from LifeSpan Bioscience
|
||||||||||
Anti-C4orf49 / OSAP Antibody (aa176-204, APC) - LS-C233312 from LifeSpan Bioscience
|
||||||||||
Anti-C4orf49 / OSAP Antibody (aa176-204, AP) - LS-C233311 from LifeSpan Bioscience
|
||||||||||
Anti-C4orf49 / OSAP Antibody (aa176-204, Biotin) - LS-C233313 from LifeSpan Bioscience
|
||||||||||
Anti-C4orf49 / OSAP Antibody (aa176-204, FITC) - LS-C233314 from LifeSpan Bioscience
|
||||||||||
Anti-C4orf49 / OSAP Antibody (aa176-204, PE) - LS-C233315 from LifeSpan Bioscience
|
||||||||||
Anti-C4orf49 / OSAP Antibody (aa176-204, Azide-free, HRP) - LS-C249558 from LifeSpan Bioscience
|
||||||||||
Anti-C4orf49 / OSAP Antibody (aa175-204) - LS-C319949 from LifeSpan Bioscience
|
||||||||||
Anti-C4orf49 / OSAP Antibody (aa186-235) - LS-C205779 from LifeSpan Bioscience
|
||||||||||
Anti-C4orf49 / OSAP Antibody (aa176-204) - LS-C168150 from LifeSpan Bioscience
|
||||||||||
OSAP Antibody - NB110-82379 from Novus Biologicals
|
||||||||||
ANTI-C4ORF49 (C-TERM) antibody produced in rabbit - SAB1302280 from Sigma-Aldrich
|
||||||||||
ENDOTHELIUM Antibody (OASA02751) - OASA02751 from Aviva Systems Biology
|
||||||||||
ENDOTHELIUM Antibody (OASA02752) - OASA02752 from Aviva Systems Biology
|
||||||||||
Rat ENDOTHELIUM Antibody (OASA04143) - OASA04143 from Aviva Systems Biology
|
||||||||||
ENDOTHELIUM Antibody (OASA04144) - OASA04144 from Aviva Systems Biology
|
||||||||||
ENDOTHELIUM Antibody (OASA04145) - OASA04145 from Aviva Systems Biology
|
||||||||||
ENDOTHELIUM Antibody (OASA04146) - OASA04146 from Aviva Systems Biology
|
||||||||||
Endothelium Antibody - FITC Conjugated (OASA04147) - OASA04147 from Aviva Systems Biology
|
||||||||||
MGARP Antibody - C-terminal region (ARP50091_P050) - ARP50091_P050 from Aviva Systems Biology
|
||||||||||
C4orf49-Antibody-C-term - AP14729b from Abgent, a WuXi AppTec company
|
||||||||||
C4orf49 Antibody - C-terminal region (OAAB11060) - OAAB11060 from Aviva Systems Biology
|