| Gene Symbol |
GALNT8
|
| Entrez Gene |
26290
|
| Alt Symbol |
GALNAC-T8
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
polypeptide N-acetylgalactosaminyltransferase 8
|
| Other Description |
GalNAc transferase 8|UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase 8|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 8|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8)|polypeptide GalNAc transferase 8|pp-GaNTase 8|probable polypeptide N-acetylgalactosaminyltransferase 8|protein-UDP acetylgalactosaminyltransferase 8
|
| Swissprots |
Q9NY28 B2RU02
|
| Accessions |
EAW88835 Q9NY28 AJ271385 CAB89199 AJ505959 CAD44539 BC140888 AAI40889 BC140889 AAI40890 NM_017417 NP_059113
|
| Function |
Probably catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. {ECO:0000250}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed. Expressed in heart, skeletal muscle, kidney, liver, small intestine and placenta. Weakly expressed in colon, thymus, spleen, lung and leukocyte. {ECO:0000269|PubMed:10767557}.
|
| Top Pathways |
Mucin type O-Glycan biosynthesis
|