Gene Symbol | GALNT8 |
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Entrez Gene | 26290 |
Alt Symbol | GALNAC-T8 |
Species | Human |
Gene Type | protein-coding |
Description | polypeptide N-acetylgalactosaminyltransferase 8 |
Other Description | GalNAc transferase 8|UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase 8|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 8|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8)|polypeptide GalNAc transferase 8|pp-GaNTase 8|probable polypeptide N-acetylgalactosaminyltransferase 8|protein-UDP acetylgalactosaminyltransferase 8 |
Swissprots | Q9NY28 B2RU02 |
Accessions | EAW88835 Q9NY28 AJ271385 CAB89199 AJ505959 CAD44539 BC140888 AAI40889 BC140889 AAI40890 NM_017417 NP_059113 |
Function | Probably catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. {ECO:0000250}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Tissue Specificity | Widely expressed. Expressed in heart, skeletal muscle, kidney, liver, small intestine and placenta. Weakly expressed in colon, thymus, spleen, lung and leukocyte. {ECO:0000269|PubMed:10767557}. |
Top Pathways | Mucin type O-Glycan biosynthesis |
GalNAc-T8 CRISPR/Cas9 KO Plasmid (h) - sc-411910 from Santa Cruz Biotechnology
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GalNAc-T8 HDR Plasmid (h) - sc-411910-HDR from Santa Cruz Biotechnology
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GalNAc-T8 Double Nickase Plasmid (h) - sc-411910-NIC from Santa Cruz Biotechnology
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GalNAc-T8 Double Nickase Plasmid (h2) - sc-411910-NIC-2 from Santa Cruz Biotechnology
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GalNAc-T8 CRISPR Activation Plasmid (h) - sc-411910-ACT from Santa Cruz Biotechnology
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GalNAc-T8 CRISPR Activation Plasmid (h2) - sc-411910-ACT-2 from Santa Cruz Biotechnology
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GalNAc-T8 Lentiviral Activation Particles (h) - sc-411910-LAC from Santa Cruz Biotechnology
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GalNAc-T8 Lentiviral Activation Particles (h2) - sc-411910-LAC-2 from Santa Cruz Biotechnology
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GalNAc-T8 siRNA (h) - sc-75102 from Santa Cruz Biotechnology
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GalNAc-T8 shRNA Plasmid (h) - sc-75102-SH from Santa Cruz Biotechnology
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GalNAc-T8 shRNA (h) Lentiviral Particles - sc-75102-V from Santa Cruz Biotechnology
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GALNT8 RNAi - H00026290-R01 from Novus Biologicals
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MISSION® esiRNA - EHU150341 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9113 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9113 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00083 from Sigma-Aldrich
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GALNT8 siRNA (Human) - CRH8809 from Cohesion Biosciences
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GALNT8 - MBS8201883 from MyBioSource
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shRNA set against Human GALNT8 (NM_017417.1) - SHH299097 from Creative biogene
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Human GALNT8 siRNA - orb269311 from Biorbyt
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GALNT8 shRNA Plasmid (Human) - CHH8809 from Cohesion Biosciences
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GALNT8 miRNA 3'UTR clone - MiUTR1H-03943 from Creative biogene
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