| Gene Symbol |
PSD
|
| Entrez Gene |
5662
|
| Alt Symbol |
EFA6, EFA6A, PSD1, TYL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
pleckstrin and Sec7 domain containing
|
| Other Description |
PH and SEC7 domain-containing protein 1|exchange factor for ARF6|pleckstrin homology and SEC7 domain-containing protein 1|pleckstrin-Sec7 domains-containing
|
| Swissprots |
B1AKX7 A5PKW4 Q8IVG0 D3DR87 Q15673
|
| Accessions |
A5PKW4 CCO13797 EAW49693 EAW49694 EAW49695 AB095931 BAC23107 AF452641 AAP97695 AI936992 BC037332 BC039259 AAH39259 BC142643 AAI42644 BC142689 AAI42690 BM920983 DB505450 XM_011539968 XP_011538270 XM_011539969 XP_011538271 NM_001270965 NP_001257894 NM_001270966 NP_001257895 NM_002779 NP_002770 NR_073110
|
| Function |
Guanine nucleotide exchange factor for ARF6. Induces cytoskeletal remodeling (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}. Cell projection, ruffle {ECO:0000250}.
|
| Tissue Specificity |
Isoform 2 is expressed in the brain. {ECO:0000269|PubMed:9417912}.
|
| Top Pathways |
Endocytosis
|