Gene Symbol | PSD |
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Entrez Gene | 5662 |
Alt Symbol | EFA6, EFA6A, PSD1, TYL |
Species | Human |
Gene Type | protein-coding |
Description | pleckstrin and Sec7 domain containing |
Other Description | PH and SEC7 domain-containing protein 1|exchange factor for ARF6|pleckstrin homology and SEC7 domain-containing protein 1|pleckstrin-Sec7 domains-containing |
Swissprots | B1AKX7 A5PKW4 Q8IVG0 D3DR87 Q15673 |
Accessions | A5PKW4 CCO13797 EAW49693 EAW49694 EAW49695 AB095931 BAC23107 AF452641 AAP97695 AI936992 BC037332 BC039259 AAH39259 BC142643 AAI42644 BC142689 AAI42690 BM920983 DB505450 XM_011539968 XP_011538270 XM_011539969 XP_011538271 NM_001270965 NP_001257894 NM_001270966 NP_001257895 NM_002779 NP_002770 NR_073110 |
Function | Guanine nucleotide exchange factor for ARF6. Induces cytoskeletal remodeling (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}. Cell projection, ruffle {ECO:0000250}. |
Tissue Specificity | Isoform 2 is expressed in the brain. {ECO:0000269|PubMed:9417912}. |
Top Pathways | Endocytosis |
PSD CRISPR/Cas9 KO Plasmid (h) - sc-410958 from Santa Cruz Biotechnology
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PSD HDR Plasmid (h) - sc-410958-HDR from Santa Cruz Biotechnology
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PSD Double Nickase Plasmid (h) - sc-410958-NIC from Santa Cruz Biotechnology
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PSD Double Nickase Plasmid (h2) - sc-410958-NIC-2 from Santa Cruz Biotechnology
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PSD CRISPR Activation Plasmid (h) - sc-410958-ACT from Santa Cruz Biotechnology
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PSD CRISPR Activation Plasmid (h2) - sc-410958-ACT-2 from Santa Cruz Biotechnology
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PSD Lentiviral Activation Particles (h) - sc-410958-LAC from Santa Cruz Biotechnology
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PSD Lentiviral Activation Particles (h2) - sc-410958-LAC-2 from Santa Cruz Biotechnology
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PSD siRNA (h) - sc-90561 from Santa Cruz Biotechnology
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PSD shRNA Plasmid (h) - sc-90561-SH from Santa Cruz Biotechnology
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PSD shRNA (h) Lentiviral Particles - sc-90561-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU090631 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17565 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17565 from Sigma-Aldrich
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PSD siRNA (Human) - CRH3816 from Cohesion Biosciences
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shRNA set against Human PSD (NM_002779.4) - SHH384814 from Creative biogene
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Human PSD siRNA - orb264318 from Biorbyt
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PSD shRNA Plasmid (Human) - CHH3816 from Cohesion Biosciences
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PSD miRNA 3'UTR clone - MiUTR3H-04885 from Creative biogene
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