| Gene Symbol |
SLC39A8
|
| Entrez Gene |
64116
|
| Alt Symbol |
BIGM103, LZT-Hs6, PP3105, ZIP8
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 39 (zinc transporter), member 8
|
| Other Description |
BCG induced integral membrane protein BIGM103|BCG-induced integral membrane protein in monocyte clone 103 protein|LIV-1 subfamily of ZIP zinc transporter 6|ZIP-8|Zrt- and Irt-like protein 8|solute carrier family 39 (metal ion transporter), member 8|solute carrier family 39 member 8|zinc transporter ZIP8
|
| Swissprots |
Q9BVC0 Q9C0K1 Q96SM9 B4E2H3 Q9NSA4
|
| Accessions |
EAX06129 EAX06130 EAX06131 EAX06132 Q9C0K1 AB020969 AB020970 BAA96442 AB040120 BAB21559 AF193052 AAG22480 AK027652 BAB55268 AK304274 BAG65135 AL049963 BC001320 AAH01320 BC012125 AAH12125 BF000600 BI823248 CA438467 DQ892212 ABM83138 DQ895407 ABM86333 DR006301 XM_005263177 XP_005263234 XM_011532181 XP_011530483 XM_011532182 XP_011530484 NM_001135146 NP_001128618 NM_001135147 NP_001128619 NM_001135148 NP_001128620 NM_022154 NP_071437
|
| Function |
Acts as a zinc-influx transporter. {ECO:0000269|PubMed:12504855}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Associated with the lysosomal/endosomal compartment following transfection. {ECO:0000269|PubMed:12504855}.
|
| Tissue Specificity |
Expressed in thymus, placenta, lung, liver, pancreas and, to a lower extent, in spleen, testis, ovary, small intestine, colon, leukocyte, heart. Highest expression is observed in pancreas. {ECO:0000269|PubMed:12504855}.
|
![Western Blot: SLC39A8/ZIP8 Overexpression Lysate (Adult Normal) [NBP2-04389] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SLC39A8/ZIP8.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/23020_SLC39A8-ZIP8%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-04389-img0001.jpg)
![Western Blot: SLC39A8/ZIP8 Overexpression Lysate (Adult Normal) [NBP2-11098] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SLC39A8/ZIP8.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2366_SLC39A8-ZIP8%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-11098-img0001.jpg)