Gene Symbol | SLC39A8 |
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Entrez Gene | 64116 |
Alt Symbol | BIGM103, LZT-Hs6, PP3105, ZIP8 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 39 (zinc transporter), member 8 |
Other Description | BCG induced integral membrane protein BIGM103|BCG-induced integral membrane protein in monocyte clone 103 protein|LIV-1 subfamily of ZIP zinc transporter 6|ZIP-8|Zrt- and Irt-like protein 8|solute carrier family 39 (metal ion transporter), member 8|solute carrier family 39 member 8|zinc transporter ZIP8 |
Swissprots | Q9BVC0 Q9C0K1 Q96SM9 B4E2H3 Q9NSA4 |
Accessions | EAX06129 EAX06130 EAX06131 EAX06132 Q9C0K1 AB020969 AB020970 BAA96442 AB040120 BAB21559 AF193052 AAG22480 AK027652 BAB55268 AK304274 BAG65135 AL049963 BC001320 AAH01320 BC012125 AAH12125 BF000600 BI823248 CA438467 DQ892212 ABM83138 DQ895407 ABM86333 DR006301 XM_005263177 XP_005263234 XM_011532181 XP_011530483 XM_011532182 XP_011530484 NM_001135146 NP_001128618 NM_001135147 NP_001128619 NM_001135148 NP_001128620 NM_022154 NP_071437 |
Function | Acts as a zinc-influx transporter. {ECO:0000269|PubMed:12504855}. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Associated with the lysosomal/endosomal compartment following transfection. {ECO:0000269|PubMed:12504855}. |
Tissue Specificity | Expressed in thymus, placenta, lung, liver, pancreas and, to a lower extent, in spleen, testis, ovary, small intestine, colon, leukocyte, heart. Highest expression is observed in pancreas. {ECO:0000269|PubMed:12504855}. |
BIGM103 CRISPR/Cas9 KO Plasmid (h) - sc-403471 from Santa Cruz Biotechnology
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BIGM103 HDR Plasmid (h) - sc-403471-HDR from Santa Cruz Biotechnology
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BIGM103 Double Nickase Plasmid (h) - sc-403471-NIC from Santa Cruz Biotechnology
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BIGM103 Double Nickase Plasmid (h2) - sc-403471-NIC-2 from Santa Cruz Biotechnology
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BIGM103 CRISPR Activation Plasmid (h) - sc-403471-ACT from Santa Cruz Biotechnology
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BIGM103 CRISPR Activation Plasmid (h2) - sc-403471-ACT-2 from Santa Cruz Biotechnology
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BIGM103 Lentiviral Activation Particles (h) - sc-403471-LAC from Santa Cruz Biotechnology
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BIGM103 Lentiviral Activation Particles (h2) - sc-403471-LAC-2 from Santa Cruz Biotechnology
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BIGM103 siRNA (h) - sc-89083 from Santa Cruz Biotechnology
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BIGM103 shRNA Plasmid (h) - sc-89083-SH from Santa Cruz Biotechnology
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BIGM103 shRNA (h) Lentiviral Particles - sc-89083-V from Santa Cruz Biotechnology
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SLC39A8/ZIP8 RNAi - H00064116-R01 from Novus Biologicals
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MISSION® esiRNA - EHU066891 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19626 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19626 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12640 from Sigma-Aldrich
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SLC39A8 siRNA (Human) - CRJ1931 from Cohesion Biosciences
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SLC39A8 - MBS8204577 from MyBioSource
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shRNA set against Human SLC39A8 (NM_022154.5) - SHH411196 from Creative biogene
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shRNA set against Human SLC39A8(NM_022154.5) - SHL008442 from Creative biogene
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Human SLC39A8 siRNA - orb272432 from Biorbyt
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SLC39A8 shRNA Plasmid (Human) - CHJ1931 from Cohesion Biosciences
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SLC39A8 miRNA 3'UTR clone - MiUTR1H-09562 from Creative biogene
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SLC39A8 miRNA 3'UTR clone - MiUTR3H-10179 from Creative biogene
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SLC39A8 miRNA 3'UTR clone - MiUTR3H-10180 from Creative biogene
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