| Gene Symbol |
LOX
|
| Entrez Gene |
4015
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
lysyl oxidase
|
| Other Description |
protein-lysine 6-oxidase
|
| Swissprots |
P28300 Q5FWF0 B2R5Q3
|
| Accessions |
AAA16870 AAA59541 AAD10703 AAK58603 AAL40853 ABO15004 EAW48898 P28300 AF039291 AAD02130 AI536895 AK297709 BAG60066 AK298781 BAG60920 AK307559 AK307732 AK311354 AK312269 BAG35200 AK315873 BAF98764 AK316309 BAH14680 BC074820 AAH74820 BC074872 AAH74872 BC089436 AAH89436 CN265862 DA461370 M94054 AAA59525 S45875 AAB23549 S78694 AAB21243 NM_001178102 NP_001171573 NM_002317 NP_002308
|
| Function |
Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. In addition to cross-linking of extracellular matrix proteins, may have a direct role in tumor suppression.
|
| Subcellular Location |
Secreted, extracellular space.
|
| Tissue Specificity |
Heart, placenta, skeletal muscle, kidney, lung and pancreas. {ECO:0000269|PubMed:7706256}.
|
![Western Blot: LOX Overexpression Lysate (Adult Normal) [NBL1-12640] - Left - Empty vector transfected control cell lysate (HEK293 cell lysate); Right - Over-expression Lysate for LOX.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/702_LOX-Overexpression-Lysate-(Adult-Normal)-Western-Blot-NBL1-12640-img0003.jpg)