LOX

Gene Symbol LOX
Entrez Gene 4015
Alt Symbol -
Species Human
Gene Type protein-coding
Description lysyl oxidase
Other Description protein-lysine 6-oxidase
Swissprots P28300 Q5FWF0 B2R5Q3
Accessions AAA16870 AAA59541 AAD10703 AAK58603 AAL40853 ABO15004 EAW48898 P28300 AF039291 AAD02130 AI536895 AK297709 BAG60066 AK298781 BAG60920 AK307559 AK307732 AK311354 AK312269 BAG35200 AK315873 BAF98764 AK316309 BAH14680 BC074820 AAH74820 BC074872 AAH74872 BC089436 AAH89436 CN265862 DA461370 M94054 AAA59525 S45875 AAB23549 S78694 AAB21243 NM_001178102 NP_001171573 NM_002317 NP_002308
Function Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. In addition to cross-linking of extracellular matrix proteins, may have a direct role in tumor suppression.
Subcellular Location Secreted, extracellular space.
Tissue Specificity Heart, placenta, skeletal muscle, kidney, lung and pancreas. {ECO:0000269|PubMed:7706256}.

LOX (F-8) - sc-373995 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LOX (F-8): sc-373995. Western blot analysis of LOX expression in WI-38 (A) and MCF7 (B) whole cell lysates.

LOX (H-140) - sc-66947 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LOX (H-140): sc-66947. Western blot analysis of LOX expression in CHO (A) and JAR (B) whole cell lysates.

LOX (V-20) - sc-32409 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LOX (V-20): sc-32409. Western blot analysis of LOX expression in WI 38 (A) and JEG-3 (B) whole cell lysates.

LOX (E-19) - sc-32410 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-LOX antibody - ab137551 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-LOX antibody (ab137551) at 1/1000 dilutionLane 1 : MCF-7 normoxia cell lysateLane 2 : MCF-7 hypoxia cell lysateLysates/proteins at 30 µg per lane.

Anti-LOX antibody - ab94991 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-LOX antibody (ab94991) at 1/100 dilution + MDA-MB468 cell line lysates at 35 µg

Anti-LOX antibody [9B5] - ab118037 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 9B5
ab118037 at 1/100 immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LOX.

Anti-LOX antibody [EPR4025] - ab174316 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4025
All lanes : Anti-LOX antibody [EPR4025] (ab174316) at 1/3700 dilution (purified)Lane 1 : WI-38 cell lysateLane 2 : Jurkat cell lysateLane 3 : Mouse brainLane 4 : Rat brainLysates/proteins at 20 µg per lane.SecondaryHRP goat anti-rabbit (H+L) at 1/1000 dilution

Anti-LOX antibody [EPR4025] (Alexa Fluor® 647) - ab197061 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4025
Overlay histogram showing HeLa cells stained with ab197061 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab197061, 1/50 dilution) for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) Alexa Fluor® 647 used at the same concentration and conditions as the primary antibody. Unlabelled sample (blue line) was also used as a control.Acquisition of >5,000 events were collected using a solid-state 25mW red diode laser (635 nm) and 675/30 bandpass filter.This antibody gave a positive signal in HeLa fixed with 4% formaldehyde (10 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-LOX antibody [EPR4025] (HRP) - ab197062 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4025
IHC image of LOX staining in a section of formalin-fixed paraffin-embedded normal human heart muscle, performed on a Leica BOND. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20mins. The section was then incubated with ab197062 at 1/100 dilution, for 15 mins at room temperature. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. The inset negative control image is taken from an identical assay without primary antibody.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-LOX / Lysyl Oxidase Antibody (Internal) - LS-C71768 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LOX / Lysyl Oxidase Antibody (aa181-196) - LS-C71730 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LOX / Lysyl Oxidase Antibody (Internal, Biotin) - LS-C141062 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LOX / Lysyl Oxidase Antibody (Internal, DY488) - LS-C141064 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LOX / Lysyl Oxidase Antibody (Internal, DY650) - LS-C141063 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Lysyl Oxidase / LOX Antibody (Internal, HRP) - LS-C141065 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LOX / Lysyl Oxidase Antibody (Internal, DY550) - LS-C141066 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LOX / Lysyl Oxidase Antibody (aa300-400, Biotin) - LS-C141072 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-LOX / Lysyl Oxidase Antibody (aa300-400, DY650) - LS-C141073 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-Lysyl Oxidase / LOX Antibody (aa300-400, HRP) - LS-C141075 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-LOX / Lysyl Oxidase Antibody (aa300-400, DY488) - LS-C141074 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-LOX / Lysyl Oxidase Antibody (aa300-400, DY550) - LS-C141076 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-LOX / Lysyl Oxidase Antibody (aa300-350, Biotin) - LS-C142774 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LOX / Lysyl Oxidase Antibody (clone 9B5) - LS-C114931 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 9B5
Anti-LOX mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LOX.

Anti-LOX / Lysyl Oxidase Antibody (clone 7E6) - LS-C114934 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 7E6
Anti-LOX mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LOX.
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