RHBDD1

Gene Symbol RHBDD1
Entrez Gene 84236
Alt Symbol RRP4
Species Human
Gene Type protein-coding
Description rhomboid domain containing 1
Other Description rhomboid domain-containing protein 1|rhomboid-like protein 4|rhomboid-related protein 4
Swissprots Q8IV60 Q53S43 Q8TEB9 Q5EBM8 Q495B9 Q6P5V8 Q9H057
Accessions AAY24060 EAW70841 EAW70842 Q8TEB9 AK026955 AK074258 BAB85031 AK093986 AL512717 CAC21658 AL832364 AY640233 AAU14246 BC015553 BC027900 AAH27900 BC062636 AAH62636 BC071679 BC089404 AAH89404 BC101262 AAI01263 BC101263 AAI01264 BC101264 AAI01265 BC101265 AAI01266 BC111056 AAI11057 CA434330 DB024396 DQ570409 JF432471 ADZ15688 XM_011511978 XP_011510280 XM_011511979 XP_011510281 XR_923036 XR_923037 XR_923038 XR_923039 XR_923040 NM_001167608 NP_001161080 NM_032276 NP_115652
Function Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded membrane proteins. Required for the degradation process of some specific misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Functions in BIK, MPZ, PKD1, PTCRA, RHO, STEAP3 and TRAC processing. Involved in the regulation of exosomal secretion; inhibits the TSAP6-mediated secretion pathway. Involved in the regulation of apoptosis; modulates BIK-mediated apoptotic activity. Also plays a role in the regulation of spermatogenesis; in
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane; Multi-pass membrane protein. Mitochondrion {ECO:0000305}.
Tissue Specificity Expressed strongly in testis.

RHBDD1 (P-12) - sc-137714 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-RHBDD1 antibody - ab106402 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RHBDD1 antibody (ab106402) at 1 µg/mlLane 1 : K562 cell lysateLane 2 : K562 cell lysate with blocking peptideLysates/proteins at 15 µg per lane.

Anti-RHBDD1 Antibody (C-Terminus) - LS-C135809 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RHBDD1 antibody LS-C135809 Western blot of Fetal Kidney lysate.

Anti-RHBDD1 Antibody (C-Terminus) - LS-C108639 from LifeSpan Bioscience

Prices $325.00, $890.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Western blot of RHBDD1 in K562 cell lysate with RHBDD1 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

RHBDD1 Antibody - NBP1-85092 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RHBDD1 Antibody [NBP1-85092] - Analysis in human cell line K562.

RRP4 Antibody - NBP1-92355 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RRP4 Antibody [NBP1-92355] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

RHBDD1 Antibody - NBP1-76248 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RHBDD1 antibody produced in rabbit - SAB3500406 from Sigma-Aldrich

Prices $348.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RHBDD1: <B>Cat. No. SAB3500406</B>: Western blot analysis of RHBDD1 in K562 cell lysate with RHBDD1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

Anti-RHBDD1 antibody produced in rabbit - HPA013972 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RHBDD1: <B>Cat. No. HPA013972</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human small intestine shows strong cytoplasmic and membranous positivity in glandular cells.

RHBDD1 antibody - C-terminal region (ARP60503_P050) - ARP60503_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RHBDD1 antibody - orb75326 from Biorbyt

Prices $723.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of K562 cell lysate at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide using RHBDD1 antibody

EXOSC2 antibody - 10R-1439 from Fitzgerald

Prices $190.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2334C3a

RHBDD1 antibody - 70R-10093 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

RHBDD1 antibody - 70R-19881 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

RHBDD1 antibody - 20869-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
HEK-293 cells were subjected to SDS PAGE followed by western blot with 20869-1-AP(RHBDD1 antibody) at dilution of 1:300

RHBDD1 antibody - AP30717PU-N from Acris Antibodies

Prices $340.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

RHBDD1 antibody - H00084236-B01P from Acris Antibodies

Prices $1,530.00
Sizes 500 µg
Host Mouse
Clonality Polyclonal

RRP4 / EXOSC2 antibody - 66099-1-Ig from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Mouse
Clonality Monoclonal
Clone 1G8B1
Immunohistochemistry of paraffin-embedded human skin cancer slide using 66099-1-Ig( EXOSC2 Antibody) at dilution of 1:50

RHBDD1 Antibody - 5525 from ProSci

Prices $79.00, $325.00
Sizes 20 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of RHBDD1 in K562 cell lysate with RHBDD1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

RHBDD1 antibody - 20869-1-AP from Proteintech Group

Prices $279.00
Sizes con: 32 μg/150μl
Host Rabbit
Clonality Polyclonal
human testis tissue were subjected to SDS PAGE followed by western blot with 20869-1-AP(RHBDD1 antibody) at dilution of 1:300

rhomboid domain containing 1 , Polyclonal Antibody - MBS719191 from MyBioSource

Prices $230.00, $500.00
Sizes 50 µl, 150 µl
Host Rabbit
Clonality Polyclonal

RHBDD1 Antibody - 254190 from ABBIOTEC

Prices $292.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

RHBDD1 Antibody - 25020 from Signalway Antibody

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of RHBDD1 in K562 cell lysate with RHBDD1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

RHBDD1 Antibody - GWB-MV970G from Genway Biotech

Prices $368.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

EXOSC2 Antibody - EPP12867 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal
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