| Gene Symbol |
CEPT1
|
| Entrez Gene |
10390
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
choline/ethanolamine phosphotransferase 1
|
| Other Description |
choline/ethanolaminephosphotransferase|choline/ethanolaminephosphotransferase 1|hCEPT1
|
| Swissprots |
Q9P0Y8 Q69YJ9 Q9Y6K0
|
| Accessions |
EAW56469 EAW56470 EAW56471 EAW56472 Q9Y6K0 AF068302 AAD25170 AF138862 AAF61194 AK023381 BAG51187 AK095229 AL832104 AL833102 CAH10403 BC032610 AAH32610 BC049196 AAH49196 BX487092 HQ447330 ADQ31816 XM_005270353 XP_005270410 XM_006710285 XP_006710348 XM_011540496 XP_011538798 XR_946518 NM_001007794 NP_001007795 NM_006090 NP_006081
|
| Function |
Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP- ethanolamine, respectively. Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity. {ECO:0000269|PubMed:10191259, ECO:0000269|PubMed:10893425}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:12221122}; Multi-pass membrane protein {ECO:0000269|PubMed:12221122}. Nucleus membrane {ECO:0000269|PubMed:12221122}; Multi-pass membrane protein {ECO:0000269|PubMed:12221122}.
|
| Tissue Specificity |
Ubiquitously expressed. {ECO:0000269|PubMed:10191259}.
|
| Top Pathways |
Ether lipid metabolism, Glycerophospholipid metabolism
|