Gene Symbol | CEPT1 |
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Entrez Gene | 10390 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | choline/ethanolamine phosphotransferase 1 |
Other Description | choline/ethanolaminephosphotransferase|choline/ethanolaminephosphotransferase 1|hCEPT1 |
Swissprots | Q9P0Y8 Q69YJ9 Q9Y6K0 |
Accessions | EAW56469 EAW56470 EAW56471 EAW56472 Q9Y6K0 AF068302 AAD25170 AF138862 AAF61194 AK023381 BAG51187 AK095229 AL832104 AL833102 CAH10403 BC032610 AAH32610 BC049196 AAH49196 BX487092 HQ447330 ADQ31816 XM_005270353 XP_005270410 XM_006710285 XP_006710348 XM_011540496 XP_011538798 XR_946518 NM_001007794 NP_001007795 NM_006090 NP_006081 |
Function | Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP- ethanolamine, respectively. Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity. {ECO:0000269|PubMed:10191259, ECO:0000269|PubMed:10893425}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:12221122}; Multi-pass membrane protein {ECO:0000269|PubMed:12221122}. Nucleus membrane {ECO:0000269|PubMed:12221122}; Multi-pass membrane protein {ECO:0000269|PubMed:12221122}. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:10191259}. |
Top Pathways | Ether lipid metabolism, Glycerophospholipid metabolism |
CEPT1 CRISPR/Cas9 KO Plasmid (h) - sc-406595 from Santa Cruz Biotechnology
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CEPT1 HDR Plasmid (h) - sc-406595-HDR from Santa Cruz Biotechnology
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CEPT1 Double Nickase Plasmid (h) - sc-406595-NIC from Santa Cruz Biotechnology
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CEPT1 Double Nickase Plasmid (h2) - sc-406595-NIC-2 from Santa Cruz Biotechnology
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CEPT1 CRISPR Activation Plasmid (h) - sc-406595-ACT from Santa Cruz Biotechnology
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CEPT1 CRISPR Activation Plasmid (h2) - sc-406595-ACT-2 from Santa Cruz Biotechnology
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CEPT1 Lentiviral Activation Particles (h) - sc-406595-LAC from Santa Cruz Biotechnology
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CEPT1 Lentiviral Activation Particles (h2) - sc-406595-LAC-2 from Santa Cruz Biotechnology
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CEPT1 siRNA (h) - sc-88215 from Santa Cruz Biotechnology
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CEPT1 shRNA Plasmid (h) - sc-88215-SH from Santa Cruz Biotechnology
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CEPT1 shRNA (h) Lentiviral Particles - sc-88215-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU064851 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5978 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5978 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07156 from Sigma-Aldrich
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CEPT1 siRNA (Human) - CRH7039 from Cohesion Biosciences
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CEPT1 - MBS8207592 from MyBioSource
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shRNA set against Human CEPT1 (NM_006090.3) - SHH262058 from Creative biogene
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shRNA set against Human CEPT1(NM_001007794.1) - SHG135565 from Creative biogene
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Human CEPT1 siRNA - orb267541 from Biorbyt
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CEPT1 shRNA Plasmid (Human) - CHH7039 from Cohesion Biosciences
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CEPT1 miRNA 3'UTR clone - MiUTR1H-02061 from Creative biogene
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CEPT1 miRNA 3'UTR clone - MiUTR3H-14430 from Creative biogene
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