| Gene Symbol |
PAM16
|
| Entrez Gene |
51025
|
| Alt Symbol |
CGI-136, MAGMAS, SMDMDM, TIM16, TIMM16
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
presequence translocase-associated motor 16 homolog (S. cerevisiae)
|
| Other Description |
magmas-like protein|mitochondria associated protein involved in granulocyte macrophage colony stimulating factor signal transduction|mitochondria-associated granulocyte macrophage CSF-signaling molecule|mitochondrial import inner membrane translocase subunit TIM16
|
| Swissprots |
Q9H5X3 Q9Y3D7 Q6I9Z3
|
| Accessions |
CAI93497 EAW85313 EAW85315 Q9Y3D7 AF151894 AAD34131 AF349455 AAL57767 AK026514 BAB15494 BC005024 AAH05024 BG715429 CR457362 CAG33643 HQ447918 ADQ32402 NM_016069 NP_057153
|
| Function |
Regulates ATP-dependent protein translocation into the mitochondrial matrix. Inhibits DNAJC19 stimulation of HSPA9/Mortalin ATPase activity. {ECO:0000269|PubMed:20053669}.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000269|PubMed:11750097, ECO:0000269|PubMed:20053669}; Peripheral membrane protein {ECO:0000269|PubMed:11750097, ECO:0000269|PubMed:20053669}; Matrix side {ECO:0000269|PubMed:11750097, ECO:0000269|PubMed:20053669}.
|
| Tissue Specificity |
Ubiquitously expressed. {ECO:0000269|PubMed:15704001}.
|
![Western Blot: Magmas Overexpression Lysate (Adult Normal) [NBL1-12822] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Magmas.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3866_Magmas%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-12822-img0002.jpg)