Gene Symbol | PAM16 |
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Entrez Gene | 51025 |
Alt Symbol | CGI-136, MAGMAS, SMDMDM, TIM16, TIMM16 |
Species | Human |
Gene Type | protein-coding |
Description | presequence translocase-associated motor 16 homolog (S. cerevisiae) |
Other Description | magmas-like protein|mitochondria associated protein involved in granulocyte macrophage colony stimulating factor signal transduction|mitochondria-associated granulocyte macrophage CSF-signaling molecule|mitochondrial import inner membrane translocase subunit TIM16 |
Swissprots | Q9H5X3 Q9Y3D7 Q6I9Z3 |
Accessions | CAI93497 EAW85313 EAW85315 Q9Y3D7 AF151894 AAD34131 AF349455 AAL57767 AK026514 BAB15494 BC005024 AAH05024 BG715429 CR457362 CAG33643 HQ447918 ADQ32402 NM_016069 NP_057153 |
Function | Regulates ATP-dependent protein translocation into the mitochondrial matrix. Inhibits DNAJC19 stimulation of HSPA9/Mortalin ATPase activity. {ECO:0000269|PubMed:20053669}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:11750097, ECO:0000269|PubMed:20053669}; Peripheral membrane protein {ECO:0000269|PubMed:11750097, ECO:0000269|PubMed:20053669}; Matrix side {ECO:0000269|PubMed:11750097, ECO:0000269|PubMed:20053669}. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:15704001}. |
Magmas CRISPR/Cas9 KO Plasmid (h) - sc-417482 from Santa Cruz Biotechnology
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Magmas HDR Plasmid (h) - sc-417482-HDR from Santa Cruz Biotechnology
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Magmas Double Nickase Plasmid (h) - sc-417482-NIC from Santa Cruz Biotechnology
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Magmas Double Nickase Plasmid (h2) - sc-417482-NIC-2 from Santa Cruz Biotechnology
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Magmas CRISPR Activation Plasmid (h) - sc-417482-ACT from Santa Cruz Biotechnology
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Magmas CRISPR Activation Plasmid (h2) - sc-417482-ACT-2 from Santa Cruz Biotechnology
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Magmas Lentiviral Activation Particles (h) - sc-417482-LAC from Santa Cruz Biotechnology
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Magmas Lentiviral Activation Particles (h2) - sc-417482-LAC-2 from Santa Cruz Biotechnology
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Magmas siRNA (h) - sc-93268 from Santa Cruz Biotechnology
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Magmas shRNA Plasmid (h) - sc-93268-SH from Santa Cruz Biotechnology
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Magmas shRNA (h) Lentiviral Particles - sc-93268-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU225361 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16299 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16299 from Sigma-Aldrich
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PAM16 siRNA (Human) - CRH9465 from Cohesion Biosciences
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shRNA set against Human PAM16 (NM_016069.9) - SHH370300 from Creative biogene
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Human PAM16 siRNA - orb269967 from Biorbyt
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PAM16 shRNA Plasmid (Human) - CHH9465 from Cohesion Biosciences
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