| Gene Symbol |
Gpr119
|
| Entrez Gene |
236781
|
| Alt Symbol |
-
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
G-protein coupled receptor 119
|
| Other Description |
G protein-coupled receptor 119|glucose-dependent insulinotropic receptor
|
| Swissprots |
Q7TQP3 Q2ABS2
|
| Accessions |
Q7TQP3 AB233291 BAE80212 AY288423 AAP72132 BC115557 AAI15558 BC115558 AAI15559 XM_006541488 XP_006541551 NM_181751 NP_861416
|
| Function |
Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway. {ECO:0000269|PubMed:17289847}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expression restricted to the beta-cells of pancreatic islets. {ECO:0000269|PubMed:17070774, ECO:0000269|PubMed:17289847}.
|
| Top Pathways |
cAMP signaling pathway
|