Gene Symbol | MPZ |
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Entrez Gene | 4359 |
Alt Symbol | CHM, CMT1, CMT1B, CMT2I, CMT2J, CMT4E, CMTDI3, CMTDID, DSS, HMSNIB, MPP, P0 |
Species | Human |
Gene Type | protein-coding |
Description | myelin protein zero |
Other Description | Charcot-Marie-Tooth neuropathy 1B|myelin peripheral protein|myelin protein P0 |
Swissprots | Q9BR67 Q92677 Q5VTH4 P25189 Q16072 |
Accessions | AAA18981 AAA20656 BAA03540 CAA83513 EAW52605 EAW52606 P25189 AK313555 BAG36330 BC006491 AAH06491 BF509916 BT006765 AAP35411 CD515400 CD515605 D10537 BAA01395 DB210759 DQ895885 ABM86811 EU176378 ABW03829 S66705 AAB28708 NM_000530 NP_000521 |
Function | Creation of an extracellular membrane face which guides the wrapping process and ultimately compacts adjacent lamellae. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | Found only in peripheral nervous system Schwann cells. |
Top Pathways | Cell adhesion molecules (CAMs) |
zero CRISPR/Cas9 KO Plasmid (h) - sc-405408 from Santa Cruz Biotechnology
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zero HDR Plasmid (h) - sc-405408-HDR from Santa Cruz Biotechnology
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zero Double Nickase Plasmid (h) - sc-405408-NIC from Santa Cruz Biotechnology
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zero Double Nickase Plasmid (h2) - sc-405408-NIC-2 from Santa Cruz Biotechnology
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zero CRISPR Activation Plasmid (h) - sc-405408-ACT from Santa Cruz Biotechnology
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zero CRISPR Activation Plasmid (h2) - sc-405408-ACT-2 from Santa Cruz Biotechnology
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zero Lentiviral Activation Particles (h) - sc-405408-LAC from Santa Cruz Biotechnology
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zero Lentiviral Activation Particles (h2) - sc-405408-LAC-2 from Santa Cruz Biotechnology
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zero siRNA (h) - sc-44194 from Santa Cruz Biotechnology
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zero shRNA Plasmid (h) - sc-44194-SH from Santa Cruz Biotechnology
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zero shRNA (h) Lentiviral Particles - sc-44194-V from Santa Cruz Biotechnology
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Myelin Protein Zero RNAi - H00004359-R01 from Novus Biologicals
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MISSION® esiRNA - EHU077251 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14517 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14517 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08147 from Sigma-Aldrich
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MPZ siRNA (Human) - CRH2962 from Cohesion Biosciences
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MPZ shRNA Plasmid (Human) - CHH2962 from Cohesion Biosciences
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