MPZ

Gene Symbol	MPZ
Entrez Gene	4359
Alt Symbol	CHM, CMT1, CMT1B, CMT2I, CMT2J, CMT4E, CMTDI3, CMTDID, DSS, HMSNIB, MPP, P0
Species	Human
Gene Type	protein-coding
Description	myelin protein zero
Other Description	Charcot-Marie-Tooth neuropathy 1B\|myelin peripheral protein\|myelin protein P0
Swissprots	Q9BR67 Q92677 Q5VTH4 P25189 Q16072
Accessions	AAA18981 AAA20656 BAA03540 CAA83513 EAW52605 EAW52606 P25189 AK313555 BAG36330 BC006491 AAH06491 BF509916 BT006765 AAP35411 CD515400 CD515605 D10537 BAA01395 DB210759 DQ895885 ABM86811 EU176378 ABW03829 S66705 AAB28708 NM_000530 NP_000521
Function	Creation of an extracellular membrane face which guides the wrapping process and ultimately compacts adjacent lamellae.
Subcellular Location	Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Found only in peripheral nervous system Schwann cells.
Top Pathways	Cell adhesion molecules (CAMs)

zero (N-20) - sc-18531 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

zero (N-20): sc-18531. Western blot analysis of zero expression in rat sciatic nerve tissue extract.

zero (C-19) - sc-18533 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

zero (C-19): sc-18533. Western blot analysis of zero expression in rat sciatic nerve tissue extract.

zero (F-20) - sc-23571 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

zero (F-20): sc-23571. Western blot analysis of zero expression in rat sciatic nerve tissue extract.

zero (H-60) - sc-50406 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

zero (H-60): sc-50406. Western blot analysis of zero expression in human spinal cord tissue extract.

Anti-Myelin Protein Zero antibody - ab31851 from Abcam

Prices	$390.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-Myelin Protein Zero antibody (ab31851) at 1 µg/ml + Mouse Sciatic Nerve Whole Tissue Lysate at 20 µgSecondaryIRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/15000 dilutionPerformed under reducing conditions.

Anti-Myelin Protein Zero antibody - ab39375 from Abcam

Prices	$379.00
Sizes	100 µl
Host	Chicken
Clonality	Polyclonal

A tissue section through an adult sciatic nerve. Myelin Protein Zero (green staining) can be seen in the myelin and Schwann cell processes surrounding the nodes of Ranvier. In this photomicrograph, rabbit antibodies against LAMP (lysozome-associated membrane glycoprotein) (red staining) serves as the counterstain, and DAPI (blue staining) allows visualization of nuclei.

Anti-Myelin Protein Zero antibody - ab134439 from Abcam

Prices	$384.00
Sizes	100 µg
Host	Chicken
Clonality	Polyclonal

Immunohistochemical analysis of an adult sciatic nerve labelling Myelin Protein Zero in the myelin and Schwann cell processes surrounding the nodes of Ranvier with ab134439 at 1/1000 dilution (green staining). Antibodies against LAMP (lysozome-associated membrane glycoprotein) (red staining) serves as the counterstain, and DAPI (blue staining) allows visualization of nuclei.

Anti-MPZ / P0 Antibody - LS-C73014 from LifeSpan Bioscience

Prices	$530.00
Sizes	250 µl
Host	Chicken
Clonality	Polyclonal

Anti-MPZ / P0 Antibody - LS-C149138 from LifeSpan Bioscience

Prices	$475.00
Sizes	200 µg
Host	Chicken
Clonality	Polyclonal

Anti-MPZ / P0 Antibody - LS-C211260 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-MPZ / P0 Antibody (HRP) - LS-C211284 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-MPZ / P0 Antibody (FITC) - LS-C211285 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-MPZ / P0 Antibody (Biotin) - LS-C211286 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-MPZ / P0 Antibody (aa224-235) - LS-C55136 from LifeSpan Bioscience

Prices	$395.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Antibody (0.1 ug/ml) staining of Rat Spinal Cord lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-MPZ / P0 Antibody - LS-C211258 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of Myelin protein P0 antibody at 2 ug/ml. Lane 1:293T whole cell lysate. Lane 2: EC109 whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 27.3 kDa. Observed band size: 27.3 kDa Additional bands at: 75 kDa. We are unsure as to the identity of this extra band.

Anti-MPZ / P0 Antibody (C-Terminus, AP) - LS-C279774 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-MPZ / P0 Antibody (C-Terminus, APC) - LS-C279775 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-MPZ / P0 Antibody (clone 3B12) - LS-C197701 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	3B12

Detection limit for recombinant GST tagged MPZ is approximately 1 ng/ml as a capture antibody.

Anti-MPZ / P0 Antibody (C-Terminus, PE) - LS-C279776 from LifeSpan Bioscience

Prices	$515.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-MPZ / P0 Antibody (HRP) - LS-C211262 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-MPZ / P0 Antibody (Biotin) - LS-C211265 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-MPZ / P0 Antibody (FITC) - LS-C211263 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-MPZ / P0 Antibody (aa30-248, Biotin) - LS-C297218 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-MPZ / P0 Antibody (aa30-248, FITC) - LS-C303386 from LifeSpan Bioscience

Prices	$425.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-MPZ / P0 Antibody (C-Terminus) - LS-C327953 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

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