SMARCB1

Gene Symbol	SMARCB1
Entrez Gene	6598
Alt Symbol	BAF47, INI1, MRD15, PPP1R144, RDT, RTPS1, SNF5, SNF5L1, SWNTS1, Sfh1p, Snr1, hSNFS
Species	Human
Gene Type	protein-coding
Description	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
Other Description	BRG1-associated factor 47|SNF5 homolog|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1|SWI/SNF-related matrix-associated protein|hSNF5|integrase interactor 1 protein|malignant rhabdoid tumor suppressor|protein phosphatase 1, regulatory subunit 144|sucrose nonfermenting, yeast, homolog-like 1
Swissprots	O95474 Q76N08 Q38GA1 Q17S11 O75784 Q9UBH2 Q12824
Accessions	AAB34227 ABB02184 CAA76639 EAW59605 EAW59606 EAW59607 EAW59608 Q12824 AB017523 BAC77068 AJ011737 CAA09758 AJ011738 CAA09759 AK021419 BAG51033 AK024025 BAB14784 AK299411 BAG61393 AK303620 BAG64629 AL389878 AL389881 AU143041 AY207470 AAO59166 AY207471 AAO59167 AY207472 AAO59168 AY562997 AAS75587 BC117114 AAI17115 BC143667 AAI43668 BG705851 CR456581 CAG30467 CU013180 CAK54611 CU013468 CAK54910 HQ258224 ADR82978 R37717 XM_011530345 XP_011528647 XM_011530346 XP_011528648 XM_011546908 XP_011545210 XM_011546909 XP_011545211 NM_001007468 NP_001007469 NM_003073 NP_003064
Function	Core component of the BAF (hSWI/SNF) complex. This ATP- dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. The BAF complex is able to create a stable, altered form of chromatin that constrains fewer negative supercoils than normal. This change in supercoiling would be due to the conversion of up to one-half of the nucleosomes on polynucleosomal arrays into asymmetric structures, termed altosomes, each composed of 2 histones octamers. Stimulates in vitro the remodeling activity of SMARCA4/BRG1/BAF190A. Involved in activation of CSF1 promoter. Belongs to the neural progenitors- specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to thei
Subcellular Location	Nucleus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SMARCB1 293T Cell Transient Overexpression Lysate(Denatured) - H00006598-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

SMARCB1 overexpression lysate - LY423489 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

SNF5 Overexpression Lysate (Denatured) - H00006598-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

SNF5 Overexpression Lysate (Native) - NBP2-04243 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

SNF5 Overexpression Lysate (Native) - NBP2-10758 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

SNF5 Overexpression Lysate (Denatured) - H00006598-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human SMARCB1 Knockdown Stable Cell Line - CSC-DC014728 from Creative biogene Category Cell Line Species Human

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