GPR84

Gene Symbol GPR84
Entrez Gene 53831
Alt Symbol EX33, GPCR4
Species Human
Gene Type protein-coding
Description G protein-coupled receptor 84
Other Description G-protein coupled receptor 84|inflammation-related G protein-coupled receptor EX33|inflammation-related G-protein coupled receptor EX33
Swissprots B6V9G7 Q9NQS5
Accessions BAB89299 EAW96776 Q9NQS5 AF237762 AAK01857 AF282693 AAF91467 AK290394 BAF83083 BC020614 AAH20614 BP303386 CD366881 DQ893217 ABM84143 DQ896546 ABM87545 FJ348261 ACI96305 XM_011538495 XP_011536797 XM_011538496 XP_011536798 NM_020370 NP_065103
Function Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system. {ECO:0000269|PubMed:16966319}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Expressed predominantly in hematopoietic tissues. High levels detected in the bone marrow and lower levels in the peripheral leukocytes and lung. Also expressed in brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta and intestine. Within the leukocyte population expression is higher in neutrophils and eosinophils relative to T- or B-lymphocytes. {ECO:0000269|PubMed:11273702, ECO:0000269|PubMed:11404393, ECO:0000269|PubMed:16966319}.

GPR84 (D-15) - sc-48221 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

GPR84 (D-16) - sc-48222 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

GPR84 (H-300) - sc-99106 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GPR84 (H-300): sc-99106. Western blot analysis of GPR84 expression in human bone marrow tissue extract.

Anti-GPCR EX33 antibody - ab188786 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain tissue, labeling GPCR EX33 with ab188786 at 106 µg/ml.

Anti-GPCR EX33 antibody - ab57238 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57238 GPCR EX33 antibody at 1ug/ml.

Anti-GPR84 Antibody (aa265-293, AP) - LS-C214905 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPR84 Antibody (aa265-293, APC) - LS-C214906 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPR84 Antibody (aa265-293, FITC) - LS-C214907 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPR84 Antibody (aa262-311) - LS-C152035 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GPR84 antibody Western Blot of Placenta.

Anti-GPR84 Antibody (aa265-293, Biotin) - LS-C214908 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPR84 Antibody (aa265-293, Azide-free, HRP) - LS-C214909 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPR84 Antibody (aa265-293, PE) - LS-C214910 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPR84 Antibody (clone 5C3) - LS-C139059 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5C3
Detection limit for recombinant GST tagged GPR84 is 1 ng/ml as a capture antibody.

Anti-GPR84 Antibody (aa209-317) - LS-C307619 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-GPR84 Antibody (Transmembrane Domain) IHC-plus™ - LS-A344 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GPR84 antibody LS-A344 IHC of human brain, astrocyte. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-GPR84 Antibody (aa264-293) - LS-C321761 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPR84 Antibody (Extracellular Domain) IHC-plus™ - LS-A343 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human, Spleen: Formalin-Fixed Paraffin-Embedded (FFPE)

Anti-GPR84 Antibody (aa265-293) - LS-C159777 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
GPR84 Antibody western blot of WiDr cell line lysates (35 ug/lane). The GPR84 antibody detected the GPR84 protein (arrow).

Anti-GPR84 Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A346 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GPR84 antibody LS-A346 IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GPR84 Antibody - NLS343 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: GPR84 Antibody [NLS343] - Analysis of anti-GPR84 antibody with human, spleen.

GPR84 Antibody - NBP1-84768 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: GPR84 Antibody [NBP1-84768] - Staining of human bone marrow shows strong cytoplasmic positivity in subsets of cells.

GPR84 Antibody - NLS344 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: GPR84 Antibody [NLS344] - Analysis of anti-GPR84 antibody with human brain, astrocyte at 53 ug/ ml.

GPR84 Antibody (1D9) - H00053831-M03 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D9
Western Blot: GPR84 Antibody (1D9) [H00053831-M03] - Analysis of GPR84 expression in transfected 293T cell line by GPR84 monoclonal antibody (M03), clone 1D9. Lane 1: GPR84 transfected lysate (Predicted MW: 43.7 KDa). Lane 2: Non-transfected lysate.

GPR84 Antibody (5B7) - H00053831-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5B7
Sandwich ELISA: GPR84 Antibody (5B7) [H00053831-M02] - Detection limit for recombinant GST tagged GPR84 is approximately 0.03ng/ml as a capture antibody.

GPR84 Antibody (5C3) - H00053831-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5C3
Western Blot: GPR84 Antibody (5C3) [H00053831-M01] - Analysis of GPR84 expression in transfected 293T cell line by GPR84 monoclonal antibody (M01), clone 5C3.Lane 1: GPR84 transfected lysate (Predicted MW: 43.7 KDa).Lane 2: Non-transfected lysate.
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