POLR2L

Gene Symbol POLR2L
Entrez Gene 5441
Alt Symbol RBP10, RPABC5, RPB10, RPB10beta, RPB7.6, hRPB7.6
Species Human
Gene Type protein-coding
Description polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
Other Description DNA-directed RNA polymerase III subunit L|DNA-directed RNA polymerases I, II, and III subunit RPABC5|RNA polymerase II 7.6 kDa subunit|RNA polymerases I, II, and III subunit ABC5|RPB10 homolog
Swissprots P62875 Q6FHX3
Accessions CAA87657 CAA87658 EAX02408 P62875 AJ420546 AK311997 BAG34935 BC005903 AAH05903 BC018649 AAH18649 BQ435190 BU679804 CR536565 CAG38802 DQ893146 ABM84072 DQ896440 ABM87439 DQ896562 ABM87561 U37690 AAA91459 NM_021128 NP_066951
Function DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2L/RBP10 is part of the core element with the central large cleft (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000269|PubMed:16809778, ECO:0000269|PubMed:9852112}.
Top Pathways Huntington's disease, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Purine metabolism, RNA polymerase

Human POLR2L full length protein - ab81843 from Abcam

Category Protein
Source E. coli
Species Human

Recombinant Human POLR2L Protein - H00005441-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

POLR2L - H00005441-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

POLR2L - H00005441-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

POLR2L fusion protein - Ag8814 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

POLR2L fusion protein - Ag8468 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human POLR2L, His-tagged - POLR2L-3056H from Creative Biomart

Category Protein
Source E.Coli.

Recombinant Human POLR2L - POLR2L-30688TH from Creative Biomart

Category Protein
Source E. coli

Recombinant Human POLR2L, GST-tagged - POLR2L-1849H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant DNA-directed RNA polymerases I, II, and III subunit RPABC5(rpb-10) - CSB-YP428211CXX CSB-EP428211CXX CSB-BP428211CXX CSB-MP428211CXX from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Caenorhabditis

Recombinant Human DNA-directed RNA polymerases I, II, and III subunit RPABC5(POLR2L) - CSB-YP018341HU CSB-EP018341HU CSB-BP018341HU CSB-MP018341HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

POLR2L - TP300649 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
POLR2L

Recombinant Human (RNA) Polymerase II hRPB10 subunit GST - CSI13976 from Cell Science

Prices $740.00
Sizes 10 μg
Species Human

Recombinant Human POLR2K GST Active - CSI13977 from Cell Science

Prices $760.00
Sizes 10 μg
Species Human

POLR2L Peptide, Human - M34GP12102H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

DNA-directed RNA polymerases I, II, and III subunit RPABC5, Recombinant Protein - MBS1355121 from MyBioSource

Category Protein
Prices $800.00, $800.00, $1,025.00, $1,025.00, $1,125.00, $1,125.00, $1,580.00, $1,580.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell

DNA-directed RNA polymerases I, II, and III subunit RPABC5 (POLR2L), Recombinant Protein - MBS961944 from MyBioSource

Category Protein
Prices $795.00, $795.00, $1,020.00, $1,020.00, $1,115.00, $1,115.00, $1,570.00, $1,570.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

DNA-directed RNA polymerases I, II, and III subunit RPABC5 (POLR2L), Recombinant Protein - MBS1475527 from MyBioSource

Category Protein
Prices $795.00, $795.00, $1,020.00, $1,020.00, $1,115.00, $1,115.00, $1,570.00, $1,570.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell

DNA-directed RNA polymerases I, II, and III subunit RPABC5 (rpb-10), Recombinant Protein - MBS1192441 from MyBioSource

Category Protein
Prices $795.00, $795.00, $1,020.00, $1,020.00, $1,115.00, $1,115.00, $1,570.00, $1,570.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Caenorhabditis

DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RPB10), Recombinant Protein - MBS1334891 from MyBioSource

Category Protein
Prices $800.00, $800.00, $1,025.00, $1,025.00, $1,120.00, $1,120.00, $1,580.00, $1,580.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Ashbya gossypii

DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RPB10), Recombinant Protein - MBS1303011 from MyBioSource

Category Protein
Prices $800.00, $800.00, $1,025.00, $1,025.00, $1,125.00, $1,125.00, $1,585.00, $1,585.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
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