KCNJ12

Gene Symbol	KCNJ12
Entrez Gene	3768
Alt Symbol	IRK-2, IRK2, KCNJN1, Kir2.2, Kir2.2v, hIRK, hIRK1, hkir2.2x, kcnj12x
Species	Human
Gene Type	protein-coding
Description	potassium channel, inwardly rectifying subfamily J, member 12
Other Description	ATP-sensitive inward rectifier potassium channel 12|inward rectifier K(+) channel Kir2.2|inward rectifier K(+) channel Kir2.2v|inward rectifier K(+) channel Kir2.6|potassium channel, inwardly rectifying subfamily J member 12|potassium inwardly-rectifying channel, subfamily J, inhibitor 1|potassium inwardly-rectifying channel, subfamily J, member 12
Swissprots	Q14500 Q15756 Q8NG63 O43401
Accessions	AAC50615 BAC02718 BAD22701 EAW49109 Q14500 AB182123 BAD23901 AF005214 AAC01951 AK024229 BC027982 AAH27982 BM799671 DA115102 JF432412 ADZ15629 L36069 AAA65122 XM_005256625 XP_005256682 XM_011523831 XP_011522133 NM_021012 NP_066292
Function	Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. {ECO:0000269|PubMed:12417321, ECO:0000269|PubMed:20921230, ECO:0000269|PubMed:7859381, ECO:0000269|PubMed:8647284}.
Subcellular Location	Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Top Pathways	Oxytocin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Anti-Kir2.2 antibody - ab121905 from Abcam Prices $443.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Kir2.2 antibody - ab45536 from Abcam Prices $242.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Kir2.2 antibody [S124B-38] - ab136888 from Abcam Prices $407.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone S124B-38

Anti-Kir2.2 antibody [S24-1] - ab84821 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S24-1

Anti-KCNJ12 / Kir2.2 Antibody (Cytoplasmic Domain) - LS-C94237 from LifeSpan Bioscience Prices $325.00 Sizes 500 µg Host Rabbit Clonality Polyclonal

Anti-KCNJ12 / Kir2.2 Antibody (Cytoplasmic Domain) - LS-C94245 from LifeSpan Bioscience Prices $325.00 Sizes 500 µg Host Rabbit Clonality Polyclonal

Anti-KCNJ12 / Kir2.2 Antibody (aa362-427) - LS-C123948 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-KCNJ12 / Kir2.2 Antibody (clone S124B/38) - LS-C152689 from LifeSpan Bioscience Prices $415.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S124B/38

Anti-KCNJ12 / Kir2.2 Antibody (aa390-410, clone S124B-38, Atto 594) - LS-C227620 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S124B-38

Anti-KCNJ12 / Kir2.2 Antibody (aa390-410, clone S124B-38, Atto 390) - LS-C227616 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S124B-38

Anti-KCNJ12 / Kir2.2 Antibody (aa390-410, clone S124B-38, Atto 488) - LS-C227618 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S124B-38

Anti-KCNJ12 / Kir2.2 Antibody (aa390-410, clone S124B-38, Atto 565) - LS-C227619 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S124B-38

Anti-KCNJ12 / Kir2.2 Antibody (aa390-410, clone S124B-38, Atto 633) - LS-C227621 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S124B-38

Anti-KCNJ12 / Kir2.2 Antibody (aa390-410, clone S124B-38, Atto 655) - LS-C227622 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S124B-38

Anti-KCNJ12 / Kir2.2 Antibody (aa390-410, clone S124B-38, Atto 680) - LS-C227623 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S124B-38

Anti-KCNJ12 / Kir2.2 Antibody (aa390-410, clone S124B-38, Atto 700) - LS-C227624 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S124B-38

Anti-KCNJ12 / Kir2.2 Antibody (aa390-410, clone S124B-38, AP) - LS-C227625 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S124B-38

Anti-KCNJ12 / Kir2.2 Antibody (aa390-410, clone S124B-38, APC) - LS-C227626 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S124B-38

Anti-KCNJ12 / Kir2.2 Antibody (aa390-410, clone S124B-38, Biotin) - LS-C227627 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S124B-38

Anti-KCNJ12 / Kir2.2 Antibody (aa390-410, clone S124B-38, FITC) - LS-C227629 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S124B-38

Anti-KCNJ12 / Kir2.2 Antibody (aa390-410, clone S124B-38, PE, Atto 594) - LS-C227630 from LifeSpan Bioscience Prices $405.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S124B-38

Anti-KCNJ12 / Kir2.2 Antibody (aa390-410, clone S124B-38, RPE) - LS-C227631 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S124B-38

Anti-KCNJ12 / Kir2.2 Antibody (aa390-410, clone S124B-38, PerCP) - LS-C227632 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S124B-38

Anti-KCNJ12 / Kir2.2 Antibody (aa390-410, clone S124B-38, SA) - LS-C227633 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone S124B-38

Anti-KCNJ12 / Kir2.2 Antibody (aa405-433, AP) - LS-C260923 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

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