| Gene Symbol |
CENPI
|
| Entrez Gene |
2491
|
| Alt Symbol |
CENP-I, FSHPRH1, LRPR1, Mis6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
centromere protein I
|
| Other Description |
FSH primary response 1|FSH primary response protein 1|follicle-stimulating hormone primary response protein|interphase centromere complex protein 19|leucine-rich primary response protein 1
|
| Swissprots |
Q96ED0 Q5JWZ9 Q92674
|
| Accessions |
CAD34792 EAX02840 EAX02841 EAX02842 EAX02843 Q92674 AK302986 BAG64126 BC005967 BC012462 AAH12462 BG114761 BQ224168 M78295 X97249 CAA65884 XM_005262111 XP_005262168 XM_011530894 XP_011529196 XM_011530895 XP_011529197 XM_011530896 XP_011529198 XM_011530897 XP_011529199 XM_011530898 XP_011529200 XM_011530899 XP_011529201 XM_011530900 XP_011529202 XM_011530901 XP_011529203 XM_011530902 XP_011529204 NM_006733 NP_006724
|
| Function |
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Required for the localization of CENPF, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. Involved in the response of gonadal tissues to follicle-stimulating hormone. {ECO:0000269|PubMed:12640463, ECO:0000269|PubMed:16622420}.
|
| Subcellular Location |
Nucleus. Chromosome, centromere. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
|