MIF

Gene Symbol	MIF
Entrez Gene	4282
Alt Symbol	GIF, GLIF, MMIF
Species	Human
Gene Type	protein-coding
Description	macrophage migration inhibitory factor (glycosylation-inhibiting factor)
Other Description	L-dopachrome isomerase|L-dopachrome tautomerase|macrophage migration inhibitory factor|phenylpyruvate tautomerase
Swissprots	Q6FHV0 B2R4S3 A5Z1R8 P14174 Q2V4Y5
Accessions	AAA21814 ABB96245 EAW59620 P14174 AF469046 AAL78635 AK311929 BAG34870 BC000447 AAH00447 BC007376 BC007676 AAH07676 BC008914 AAH08914 BC013976 AAH13976 BC022414 AAH22414 BC051440 BC053376 AAH53376 BT007148 AAP35812 CR407644 CAG28572 CR456520 CAG30406 CR541651 CAG46452 CU013120 CAK54551 CU013408 CAK54850 DQ892195 ABM83121 DQ895390 ABM86316 JQ846015 AFM09726 L10612 AAA35892 M25639 AAA36315 M95775 AAA36179 Z23063 CAA80598 NM_002415 NP_002406
Function	Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti- inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. {ECO:0000269|PubMed:15908412, ECO:0000269|PubMed:17443469, ECO:0000269|PubMed:23776208}.
Subcellular Location	Secreted. Cytoplasm. Note=Does not have a cleavable signal sequence and is secreted via a specialized, non- classical pathway. Secreted by macrophages upon stimulation by bacterial lipopolysaccharide (LPS), or by M.tuberculosis antigens.
Top Pathways	Phenylalanine metabolism, Tyrosine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human MIF full length protein - ab75432 from Abcam Category Protein Prices $239.00 Sizes 5 µg Source E. coli Species Human

Active human MIF full length protein - ab123772 from Abcam Category Protein Prices $1,075.00 Sizes 100 µg Source E. coli Species Human

Active human MIF full length protein - ab192161 from Abcam Category Protein Source E. coli Species Human

Active mouse MIF full length protein - ab191658 from Abcam Category Protein Prices $192.00 Sizes 25 µg Source E. coli Species Mouse

Chicken MIF full length protein - ab88204 from Abcam Category Protein Prices $235.00 Sizes 25 µg Source Saccharomyces cerevisiae Species Chicken

Human MIF full length protein - ab202245 from Abcam Category Protein Source E. coli Species Human

Human MIF full length protein - ab51096 from Abcam Category Protein Source E. coli Species Human

Human MIF full length protein - ab48999 from Abcam Category Protein Source E. coli Species Human

Human MIF full length protein - ab73230 from Abcam Category Protein Source E. coli Species Human

Mouse MIF full length protein - ab202262 from Abcam Category Protein Source E. coli Species Mouse

MIF (Active) recombinant protein - GTX65173 from GeneTex Category Protein Prices $299.00 Sizes 10 μg Source E. coli Species Human

MIF blocking peptide - GTX89535-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat

Recombinant Human MIF - 289-MF-002 from R&D Systems Category Protein Source E. coli-derived, Pro2-Ala115, with an N-terminal Met

Recombinant human Macrophage migration inhibitory factor (OPCA00672) - OPCA00672 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

MIF Protein His N (OPPA00690) - OPPA00690 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

MIF Protein His C (OPPA01502) - OPPA01502 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

MIF Protein (OPPA01647) - OPPA01647 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

MIF Protein (OPPA01648) - OPPA01648 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg

Human MIF protein - orb180337 from Biorbyt Category Protein Prices $408.00, $595.00, $2,074.00, $2,933.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human GLIF protein - orb245308 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

MIF (MIF Human) protein - orb176026 from Biorbyt Category Protein Prices $349.00, $434.00 Sizes 5 μl, 25 μl Species Human

MIF protein (His tag) - 80R-1007 from Fitzgerald Category Protein Prices $180.00 Sizes 100 µg Source E.coli

MIF protein - 30R-2203 from Fitzgerald Category Protein Prices $295.00, $825.00 Sizes 5 µg, 25 µg Source E.coli

MIF protein - 30R-1149 from Fitzgerald Category Protein Prices $395.00 Sizes 100 µg Source E.coli

SCF protein - 30R-1145 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

Search more