| Gene Symbol |
ELP4
|
| Entrez Gene |
26610
|
| Alt Symbol |
AN, C11orf19, PAX6NEB, PAXNEB, dJ68P15A.1, hELP4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
elongator acetyltransferase complex subunit 4
|
| Other Description |
PAX6 neighbor gene protein|elongation protein 4 homolog|elongator complex protein 4
|
| Swissprots |
Q9NX11 Q96EB1 B4E3W0 Q9H4E8 E7EPZ6
|
| Accessions |
CAC08200 CAC10331 EAW68237 EAW68238 Q96EB1 AK000505 BAA91212 AK304885 BAG65622 AL136677 CAB66612 AM393460 CAL38337 AM393857 CAL38732 BC012514 AAH12514 BF969161 BM680240 BQ083338 D59285 DQ891468 ABM82394 DQ894651 ABM85577 HY127287 XM_005252865 XP_005252922 XM_011519986 XP_011518288 XM_011519987 XP_011518289 XM_011519988 XP_011518290 XM_011519989 XP_011518291 NM_001288725 NP_001275654 NM_001288726 NP_001275655 NM_019040 NP_061913
|
| Function |
Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. {ECO:0000269|PubMed:11714725, ECO:0000269|PubMed:11818576, ECO:0000269|PubMed:16713582}.
|
| Subcellular Location |
Cytoplasm. Nucleus.
|
| Tissue Specificity |
Widely expressed. {ECO:0000269|PubMed:11889558}.
|
![Western Blot: Elp4 Overexpression Lysate (Adult Normal) [NBL1-10249] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Elp4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3186_Elp4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10249-img0002.jpg)