Gene Symbol | ELP4 |
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Entrez Gene | 26610 |
Alt Symbol | AN, C11orf19, PAX6NEB, PAXNEB, dJ68P15A.1, hELP4 |
Species | Human |
Gene Type | protein-coding |
Description | elongator acetyltransferase complex subunit 4 |
Other Description | PAX6 neighbor gene protein|elongation protein 4 homolog|elongator complex protein 4 |
Swissprots | Q9NX11 Q96EB1 B4E3W0 Q9H4E8 E7EPZ6 |
Accessions | CAC08200 CAC10331 EAW68237 EAW68238 Q96EB1 AK000505 BAA91212 AK304885 BAG65622 AL136677 CAB66612 AM393460 CAL38337 AM393857 CAL38732 BC012514 AAH12514 BF969161 BM680240 BQ083338 D59285 DQ891468 ABM82394 DQ894651 ABM85577 HY127287 XM_005252865 XP_005252922 XM_011519986 XP_011518288 XM_011519987 XP_011518289 XM_011519988 XP_011518290 XM_011519989 XP_011518291 NM_001288725 NP_001275654 NM_001288726 NP_001275655 NM_019040 NP_061913 |
Function | Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. {ECO:0000269|PubMed:11714725, ECO:0000269|PubMed:11818576, ECO:0000269|PubMed:16713582}. |
Subcellular Location | Cytoplasm. Nucleus. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:11889558}. |
ELP4 CRISPR/Cas9 KO Plasmid (h) - sc-411927 from Santa Cruz Biotechnology
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ELP4 HDR Plasmid (h) - sc-411927-HDR from Santa Cruz Biotechnology
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ELP4 Double Nickase Plasmid (h) - sc-411927-NIC from Santa Cruz Biotechnology
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ELP4 Double Nickase Plasmid (h2) - sc-411927-NIC-2 from Santa Cruz Biotechnology
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ELP4 CRISPR Activation Plasmid (h) - sc-411927-ACT from Santa Cruz Biotechnology
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ELP4 CRISPR Activation Plasmid (h2) - sc-411927-ACT-2 from Santa Cruz Biotechnology
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ELP4 Lentiviral Activation Particles (h) - sc-411927-LAC from Santa Cruz Biotechnology
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ELP4 Lentiviral Activation Particles (h2) - sc-411927-LAC-2 from Santa Cruz Biotechnology
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ELP4 siRNA (h) - sc-96714 from Santa Cruz Biotechnology
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ELP4 shRNA Plasmid (h) - sc-96714-SH from Santa Cruz Biotechnology
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ELP4 shRNA (h) Lentiviral Particles - sc-96714-V from Santa Cruz Biotechnology
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Elp4 RNAi - H00026610-R01 from Novus Biologicals
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MISSION® esiRNA - EHU072501 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7829 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7829 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01887 from Sigma-Aldrich
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ELP4 siRNA (Human) - CRH8876 from Cohesion Biosciences
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ELP4 - MBS8207875 from MyBioSource
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shRNA set against Human ELP4 (NM_019040.3) - SHH285349 from Creative biogene
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shRNA set against Human ELP4(NM_019040.3) - SHH031979 from Creative biogene
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Human ELP4 siRNA - orb269378 from Biorbyt
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ELP4 shRNA Plasmid (Human) - CHH8876 from Cohesion Biosciences
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ELP4 miRNA 3'UTR clone - MiUTR1H-03208 from Creative biogene
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