| Gene Symbol |
TMBIM4
|
| Entrez Gene |
51643
|
| Alt Symbol |
CGI-119, GAAP, LFG4, S1R, ZPRO
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transmembrane BAX inhibitor motif containing 4
|
| Other Description |
Golgi anti-apoptotic protein|Z-protein|protein lifeguard 4|transmembrane BAX inhibitor motif-containing protein 4
|
| Swissprots |
Q9HC24 Q9Y3C2 Q9UHY5 Q542Z6
|
| Accessions |
CAF86277 EAW97158 EAW97159 EAW97160 EAW97161 EAW97162 Q9HC24 AF113127 AAF14868 AF151877 AAD34114 AF161526 AAF29141 AF182041 AAG16898 AF182414 AAG14950 AK075069 BAC11384 AK127285 AK225158 AL117550 BC004401 AAH04401 BC020613 BC052273 BC070366 BC094852 BC148528 AAI48529 BC156584 AAI56585 BG534013 BM989676 DC361259 NM_001282606 NP_001269535 NM_001282609 NP_001269538 NM_001282610 NP_001269539 NM_016056 NP_057140
|
| Function |
Anti-apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli. Can modulate both capacitative Ca2+ entry and inositol 1,4,5-trisphosphate (IP3)-mediated Ca2+ release. {ECO:0000269|PubMed:17319741, ECO:0000269|PubMed:19553469}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000269|PubMed:17319741, ECO:0000269|PubMed:22418439}; Multi- pass membrane protein {ECO:0000269|PubMed:17319741, ECO:0000269|PubMed:22418439}.
|