TSEN15

Gene Symbol	TSEN15
Entrez Gene	116461
Alt Symbol	C1orf19, sen15
Species	Human
Gene Type	protein-coding
Description	TSEN15 tRNA splicing endonuclease subunit
Other Description	tRNA splicing endonuclease 15 homolog|tRNA-intron endonuclease Sen15|tRNA-splicing endonuclease subunit Sen15
Swissprots	Q9BZQ5 B4DKP0 Q8WW01
Accessions	EAW91173 EAW91174 EAW91175 Q8WW01 AF288394 AAG60614 AK098196 BAG53590 AK296655 BAG59252 AK307241 BC022030 AAH22030 BG285158 BI821111 BM146150 BM789892 BM887891 BP326115 BU195337 CB158796 HQ448688 ADQ33166 XM_006711148 XP_006711211 XM_011509139 XP_011507441 NM_001127394 NP_001120866 NM_001300764 NP_001287693 NM_001300766 NP_001287695 NM_052965 NP_443197 NR_023349 NR_125335
Function	Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events. {ECO:0000269|PubMed:15109492}.
Subcellular Location	Nucleus {ECO:0000305}. Nucleus, nucleolus {ECO:0000305}. Note=May be transiently localized in the nucleolus. {ECO:0000305}.
Tissue Specificity	Widely expressed. Highly expressed in testis and uterus. {ECO:0000269|PubMed:11318611}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human C1orf19 full length protein - ab124991 from Abcam Category Protein Prices $188.00 Sizes 10 µg Source E. coli Species Human

sen15 Partial Recombinant Protein - H00116461-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

sen15 Recombinant Protein - H00116461-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human sen15 Protein - NBP1-72318 from Novus Biologicals Category Protein Prices $349.00 Sizes 50 µg Source E. coli Species Human

TSEN15 Protein (OPPA00083) - OPPA00083 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source Escherichia Coli.

Human TSEN15 protein - orb169479 from Biorbyt Category Protein Prices $230.00, $442.00 Sizes 2 μg, 10 μg Source E. coli Species Human

TSEN15 protein (His tag) - 80R-1829 from Fitzgerald Category Protein Prices $340.00 Sizes 50 µg Source E.coli

TSEN15 (1-171, His-tag) - AR39012PU-L from Acris Antibodies Category Protein Prices $1,020.00 Sizes 250 µg Source E. coli Species Human

TSEN15 (1-171, His-tag) - AR39012PU-N from Acris Antibodies Category Protein Prices $420.00 Sizes 50 µg Source E. coli Species Human

TSEN15 - H00116461-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

TSEN15 - H00116461-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

TSEN15 - H00116461-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TSEN15 - H00116461-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TSEN15, 1-171aa, Human, His tag, E.coli - 01-P1072 from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Human

TSEN15 Human - PRPS-151 from NeoScientific Category Protein Prices $65.00, $169.00, $6,760.00 Sizes 2 µg, 10 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human tRNA Splicing Endonuclease 15 Enzyme - BP002531-PRO-144 from Syd Labs Category Protein Prices $160.00, $5,200.00 Sizes 10 µg, 1 mg Source E. coli-derived. Species Human

TSEN15, 1-171aa, Recombinant Protein - GWB-P0966D from Genway Biotech Category Protein Prices $400.00, $1,200.00 Sizes 50 μg, 250 μg Source E.coli Species Human

TSEN15 Human Protein - GWB-BSP701 from Genway Biotech Category Protein Prices $75.00, $165.00, $6,190.00 Sizes 2 μg, 10 μg, 1000 μg Source Escherichia Coli. Species Human

Recombinant Human tRNA Splicing Endonuclease 15 Homolog (S. cerevisiae), His-tagged - TSEN15-1787H from Creative Biomart Category Protein Source Human

Recombinant Human TSEN15, His-tagged - TSEN15-997H from Creative Biomart Category Protein

Recombinant Human TSEN15 tRNA splicing endonuclease subunit, His-tagged - TSEN15-693H from Creative Biomart Category Protein Source E.coli Species Human

TSEN15 - NKX-599 from Reagent Proteins Category Protein Prices $364.00, $5,334.00 Sizes 10.00 µg, 1 mg Source E.coli

TSEN15 1-171aa - CMB-905 from Reagent Proteins Category Protein Prices $539.00, $1,099.00 Sizes 50.00 µg, 250.00 µg Source E.coli Species Human

Recombinant Human tRNA-splicing endonuclease subunit Sen15(TSEN15) - CSB-YP840989HU CSB-EP840989HU CSB-BP840989HU CSB-MP840989HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TSEN15, 1-171aa, Human, His tag, E.coli - ATGP1072 from ATGen Category Protein Prices $105.00, $320.00, $960.00 Sizes 10 µg, 50 µg, 250 µg Species Human

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