| Gene Symbol |
LAMA3
|
| Entrez Gene |
3909
|
| Alt Symbol |
BM600, E170, LAMNA, LOCS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
laminin, alpha 3
|
| Other Description |
BM600 150kD subunit|LAM3, alpha-3 subunit|epiligrin 170 kda subunit|epiligrin alpha 3 subunit|kalinin 165kD subunit|kalinin subunit alpha|laminin 5, alpha-3 subunit|laminin A3|laminin subunit alpha-3|laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin)|laminin-5 alpha 3 chain|laminin-5 subunit alpha|laminin-6 subunit alpha|laminin-7 subunit alpha|nicein 150kD subunit|nicein subunit alpha
|
| Swissprots |
Q76E14 Q6VU68 Q13680 Q96TG0 B0YJ33 Q6VU69 Q16787 Q13679 Q6VU67
|
| Accessions |
AAK69483 ACA06010 ACA06011 CCQ42975 Q16787 AA001432 AB107369 BAD13428 AB208853 BAD92090 AF005258 AAC51867 AI125611 AK024889 AK096422 AY327114 AAQ72569 AY327115 AAQ72570 AY327116 AAQ72571 BC033663 AAH33663 BC043618 BC093406 AAH93406 BC172402 AAI72402 BC172580 AAI72580 CA427431 CB990144 DA862923 L34155 AAA59483 L34156 AAA59484 X84392 CAA59114 X84900 CAA59325 X85107 CAA59428 X85108 CAA59429 XM_011525978 XP_011524280 XM_011525979 XP_011524281 XM_011525980 XP_011524282 XM_011525981 XP_011524283 XM_011525982 XP_011524284 NM_000227 NP_000218 NM_001127717 NP_001121189 NM_001127718 NP_001121190 NM_001302996 NP_001289925 NM_198129 NP_937762 NR_130106
|
| Function |
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.
|
| Tissue Specificity |
Skin; respiratory, urinary, and digestive epithelia and in other specialized tissues with prominent secretory or protective functions. Epithelial basement membrane, and epithelial cell tongue that migrates into a wound bed. A differential and focal expression of the subunit alpha-3 is observed in the CNS.
|
| Top Pathways |
Focal adhesion, ECM-receptor interaction, Small cell lung cancer, Amoebiasis, Toxoplasmosis
|
![Western Blot: Laminin alpha 3 Overexpression Lysate (Adult Normal) [NBL1-12428] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Laminin alpha 3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3476_Laminin%2520alpha%25203%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-12428-img0002.jpg)