LAMA3

Gene Symbol	LAMA3
Entrez Gene	3909
Alt Symbol	BM600, E170, LAMNA, LOCS
Species	Human
Gene Type	protein-coding
Description	laminin, alpha 3
Other Description	BM600 150kD subunit\|LAM3, alpha-3 subunit\|epiligrin 170 kda subunit\|epiligrin alpha 3 subunit\|kalinin 165kD subunit\|kalinin subunit alpha\|laminin 5, alpha-3 subunit\|laminin A3\|laminin subunit alpha-3\|laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin)\|laminin-5 alpha 3 chain\|laminin-5 subunit alpha\|laminin-6 subunit alpha\|laminin-7 subunit alpha\|nicein 150kD subunit\|nicein subunit alpha
Swissprots	Q76E14 Q6VU68 Q13680 Q96TG0 B0YJ33 Q6VU69 Q16787 Q13679 Q6VU67
Accessions	AAK69483 ACA06010 ACA06011 CCQ42975 Q16787 AA001432 AB107369 BAD13428 AB208853 BAD92090 AF005258 AAC51867 AI125611 AK024889 AK096422 AY327114 AAQ72569 AY327115 AAQ72570 AY327116 AAQ72571 BC033663 AAH33663 BC043618 BC093406 AAH93406 BC172402 AAI72402 BC172580 AAI72580 CA427431 CB990144 DA862923 L34155 AAA59483 L34156 AAA59484 X84392 CAA59114 X84900 CAA59325 X85107 CAA59428 X85108 CAA59429 XM_011525978 XP_011524280 XM_011525979 XP_011524281 XM_011525980 XP_011524282 XM_011525981 XP_011524283 XM_011525982 XP_011524284 NM_000227 NP_000218 NM_001127717 NP_001121189 NM_001127718 NP_001121190 NM_001302996 NP_001289925 NM_198129 NP_937762 NR_130106
Function	Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Subcellular Location	Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.
Tissue Specificity	Skin; respiratory, urinary, and digestive epithelia and in other specialized tissues with prominent secretory or protective functions. Epithelial basement membrane, and epithelial cell tongue that migrates into a wound bed. A differential and focal expression of the subunit alpha-3 is observed in the CNS.
Top Pathways	Focal adhesion, ECM-receptor interaction, Small cell lung cancer, Amoebiasis, Toxoplasmosis

Laminin α-3 (C-19) - sc-16585 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Laminin α-3 (C-19): sc-16585. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

Laminin α-3 (H-187) - sc-20143 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

Laminin α-3 (H-187): sc-20143. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing cytoplasmic staining of glandular cells.

Laminin α-3 (N-20) - sc-16583 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Laminin α-3 (N-20): sc-16583. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

Anti-Laminin 5 alpha 3 antibody [EPR8266] - ab151715 from Abcam

Prices	$357.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR8266

All lanes : Anti-Laminin 5 alpha 3 antibody [EPR8266] (ab151715) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : HepG2 cell lysateLane 3 : A431 cell lysateLane 4 : Human skin lysateLane 5 : SH-SY5Y cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-Laminin 5 antibody - ab14509 from Abcam

Prices	$395.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-Laminin 5 antibody - ab102539 from Abcam

Prices	$376.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-Laminin 5 antibody (ab102539) at 1 µg/mlLane 1 : NIH 3T3 (Mouse embryonic fibroblast cell line) Whole Cell LysateLane 2 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Laminin 5 antibody - ab55415 from Abcam

Prices	$378.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-Laminin 5 antibody - ab97765 from Abcam

Prices	$376.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

Anti-Laminin 5 antibody (ab97765) at 1/1000 dilution + A431 whole cell lysate at 30 µg

Anti-Laminin 5 antibody [P3E4] - ab78746 from Abcam

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	P3E4

Anti-Laminin 5 antibody [P3H9-2] - ab78286 from Abcam

Prices	$390.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	P3H9-2

ab78286 staining Laminin 5 in Human cultured skin (NHEK, NB1RGB) tissue sections by Immunohistochemistry (IHC-Fr - frozen sections). Tissue was fixed with formaldehyde, permeabilized with 0.1% Triton X-100 and blocked with 10% Blocking One® for 1 hour at 25°C. Samples were incubated with primary antibody (1/500 in 10% Blocking One® in PBS) for 1 hour at 25°C. An Alexa Fluor® 555-conjugated Rabbit anti-mouse IgG polyclonal (1/200) was used as the secondary antibody.See Abreview

Anti-Laminin 5 antibody [P3H9-2] - BSA and Azide free - ab174717 from Abcam

Prices	$373.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	P3H9-2

Anti-LAMA3 / Laminin Alpha 3 Antibody (aa1462-1474) - LS-C55049 from LifeSpan Bioscience

Prices	$335.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Anti-LAMA3 / Laminin Alpha 3 Antibody (aa47-296, Biotin) - LS-C298127 from LifeSpan Bioscience

Prices	$425.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-LAMA3 / Laminin Alpha 3 Antibody (aa47-296, FITC) - LS-C302239 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-LAMA3 / Laminin Alpha 3 Antibody (aa47-296) - LS-C295078 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of recombinant LAMA3 / Laminin Alpha 3.

Anti-LAMA3 / Laminin Alpha 3 Antibody (aa2571-2620) - LS-C119559 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

IHC of paraffin-embedded human colon carcinoma tissue, using LAMA3 Antibody. The picture on the right is treated with the synthesized peptide.

Laminin alpha 3/Laminin-5 Antibody (P3H9-2) [Unconjugated] - MAB2144 from Novus Biologicals

Prices	$99.00, $249.00
Sizes	25 µg, 250 µg
Host	Mouse
Clonality	Monoclonal
Clone	P3H9-2

Laminin alpha 3/Laminin-5 was detected in immersion fixed MCF 10A human breast epithelial cell line using 10 µg/mL Mouse Anti-Human Laminin alpha 3/Laminin-5 Monoclonal Antibody (Catalog # MAB2144) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Laminin alpha 3/Laminin-5 Antibody (546215) - MAB21441 from Novus Biologicals

Prices	$99.00, $269.00
Sizes	25 µg, 100 µg
Host	Mouse
Clonality	Monoclonal
Clone	546215

Western blot shows lysates of human lung tissue. PVDF Membrane was probed with 2 µg/mL of Mouse Anti-Human Laminin alpha 3/Laminin‑5 Monoclonal Antibody (Catalog # MAB21441) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for Laminin alpha 3/Laminin‑5 at approximately 190 kDa (as indicated). This experiment was conducted under non-reducing conditions and using Immunoblot Buffer Group 1.

Laminin alpha 3 Antibody - H00003909-A01 from Novus Biologicals

Prices	$269.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Laminin alpha 3 Antibody - NB100-2469 from Novus Biologicals

Prices	$229.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

LAMA3/Laminin 5 alpha 3 Antibody - bs-1969R from Bioss

Prices	$269.00
Sizes	100 µl
Host	Rabbit

Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-LAMA3/Laminin 5 alpha 3 Polyclonal Antibody, Unconjugated (bs-1969R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Anti-LAMA3 antibody produced in rabbit - HPA009309 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-LAMA3: <B>Cat. No. HPA009309</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human vulva/anal skin tissue showing positive staining of basement membrane.

LAMA3-Antibody-internal-region - AF2485a from Abgent, a WuXi AppTec company

Prices	$325.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

LAMA3 antibody, Internal - GTX89434 from GeneTex

Prices	$239.00
Sizes	100 μg
Host	Goat
Clonality	Polyclonal

Human Laminin alpha 3/Laminin-5 Antibody - MAB2144 from R&D Systems

Prices	$99.00, $249.00
Sizes	25 µg, 250 µg
Host	Mouse
Clone	P3H9-2

Laminin a3/Laminin-5 in MCF 10A Human Cell Line. Laminin a3/Laminin-5 was detected in immersion fixed MCF 10A human breast epithelial cell line using 10 µg/mL Mouse Anti-Human Laminin a3/Laminin-5 Monoclonal Antibody (Catalog # MAB2144) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007 ) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips .

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