TLR8

Gene Symbol	TLR8
Entrez Gene	51311
Alt Symbol	CD288
Species	Human
Gene Type	protein-coding
Description	toll-like receptor 8
Other Description	-
Swissprots	D1CS76 B3Y654 D1CS70 Q9NR97 Q6UXL6 Q9NYG9 Q495P4
Accessions	AAZ95433 AAZ95434 AAZ95435 AAZ95436 AAZ95437 AAZ95438 AAZ95439 AAZ95440 AAZ95441 EAW98808 EAW98809 Q9NR97 AB445666 BAG55063 AF245703 AAF78036 AF246971 AAF64061 AK075117 BAC11412 AK297024 BAG59554 AK307562 AK314240 AY358296 AAQ88663 BC101074 AAI01075 BC101075 AAI01076 BC101076 AAI01077 BC101077 AAI01078 XM_011545529 XP_011543831 XM_011545530 XP_011543832 NM_016610 NP_057694 NM_138636 NP_619542
Function	Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. {ECO:0000269|PubMed:17932028, ECO:0000269|PubMed:23520111}.
Subcellular Location	Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity	Detected in brain, heart, lung, liver, placenta, in monocytes, and at lower levels in CD11c+ immature dendritic cells.
Top Pathways	Toll-like receptor signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TLR8 full length protein - ab153344 from Abcam Category Protein Source Wheat germ Species Human

Human TLR8 peptide - ab40021 from Abcam Category Peptide Species Human

TLR8 Antibody Blocking Peptide - LS-E2885 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TLR8 Antibody Blocking Peptide - LS-E21601 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TLR8 Antibody Blocking Peptide - LS-E30056 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TLR8 Antibody Blocking Peptide - LS-E30059 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human TLR8 Protein - H00051311-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

TLR8 Blocking Peptide - NBP1-77203PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

TLR8 Recombinant Protein - H00051311-G01 from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

TLR8-Antibody-Center-Blocking-peptide - BP14012c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant human Toll-like receptor 8 (OPCA01314) - OPCA01314 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human TLR8 protein - orb246018 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

TLR8 Blocking Peptide - 33R-10802 from Fitzgerald Category Peptide Prices $115.00 Sizes 50 µg

TLR8 Blocking Peptide - 33R-4922 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human Toll Like Receptor 8 Protein - abx069374 from Abbexa Category Protein Source E.coli Species Human

CD288 / TLR8 - H00051311-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

CD288 / TLR8 - H00051311-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

CD288 / TLR8 Control Peptide - AP30906CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

CD288 / TLR8 (N-term) Control Peptide - AP55651CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

CD288 / TLR8 (C-term) Control Peptide - AP55652CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Toll Like Receptor 8 (TLR8), Human - 20-8244 from ARP American Research Products Category Protein Prices $419.00 Sizes 50 µg Source E.coli Species Human

TLR8 Peptide - 3281P from ProSci Category Peptide Species Human

TLR8 Peptide - 3279P from ProSci Category Peptide Species Human

TLR8 Peptide - 3271P from ProSci Category Peptide Species Human

TLR8 fusion protein - ag15699 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

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