Gene Symbol |
CXCL13
|
Entrez Gene |
10563
|
Alt Symbol |
ANGIE, ANGIE2, BCA-1, BCA1, BLC, BLR1L, SCYB13
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
chemokine (C-X-C motif) ligand 13
|
Other Description |
B-cell chemoattractant|B-cell-attracting chemokine 1|B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1)|B-lymphocyte chemoattractant|C-X-C motif chemokine 13|CXC chemokine BLC|b cell-attracting chemokine 1|b lymphocyte chemoattractant|chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant)|small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant)|small-inducible cytokine B13
|
Swissprots |
O43927
|
Accessions |
AAY40955 ABK41926 EAX05816 EAX05817 O43927 AF029894 AAC17980 AF044197 AAC14402 AJ002211 CAA05250 BC012589 AAH12589 BI836728 CA418514 CR407624 CAG28552 HQ448702 ADQ33180 XM_006714063 XP_006714126 NM_006419 NP_006410
|
Function |
Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B- lymphocytes. Binds to BLR1/CXCR5.
|
Subcellular Location |
Secreted.
|
Tissue Specificity |
Highest levels in liver, followed by spleen, lymph node, appendix and stomach. Low levels in salivary gland, mammary gland and fetal spleen.
|
Top Pathways |
Cytokine-cytokine receptor interaction, Chemokine signaling pathway
|