Gene Symbol | CXCL13 |
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Entrez Gene | 10563 |
Alt Symbol | ANGIE, ANGIE2, BCA-1, BCA1, BLC, BLR1L, SCYB13 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-X-C motif) ligand 13 |
Other Description | B-cell chemoattractant|B-cell-attracting chemokine 1|B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1)|B-lymphocyte chemoattractant|C-X-C motif chemokine 13|CXC chemokine BLC|b cell-attracting chemokine 1|b lymphocyte chemoattractant|chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant)|small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant)|small-inducible cytokine B13 |
Swissprots | O43927 |
Accessions | AAY40955 ABK41926 EAX05816 EAX05817 O43927 AF029894 AAC17980 AF044197 AAC14402 AJ002211 CAA05250 BC012589 AAH12589 BI836728 CA418514 CR407624 CAG28552 HQ448702 ADQ33180 XM_006714063 XP_006714126 NM_006419 NP_006410 |
Function | Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B- lymphocytes. Binds to BLR1/CXCR5. |
Subcellular Location | Secreted. |
Tissue Specificity | Highest levels in liver, followed by spleen, lymph node, appendix and stomach. Low levels in salivary gland, mammary gland and fetal spleen. |
Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |
BLC CRISPR/Cas9 KO Plasmid (h) - sc-407761 from Santa Cruz Biotechnology
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BLC HDR Plasmid (h) - sc-407761-HDR from Santa Cruz Biotechnology
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BLC Double Nickase Plasmid (h) - sc-407761-NIC from Santa Cruz Biotechnology
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BLC Double Nickase Plasmid (h2) - sc-407761-NIC-2 from Santa Cruz Biotechnology
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BLC CRISPR Activation Plasmid (h) - sc-407761-ACT from Santa Cruz Biotechnology
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BLC CRISPR Activation Plasmid (h2) - sc-407761-ACT-2 from Santa Cruz Biotechnology
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BLC Lentiviral Activation Particles (h) - sc-407761-LAC from Santa Cruz Biotechnology
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BLC Lentiviral Activation Particles (h2) - sc-407761-LAC-2 from Santa Cruz Biotechnology
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BLC siRNA (h) - sc-39344 from Santa Cruz Biotechnology
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BLC shRNA Plasmid (h) - sc-39344-SH from Santa Cruz Biotechnology
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BLC shRNA (h) Lentiviral Particles - sc-39344-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU042121 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6800 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6800 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07070 from Sigma-Aldrich
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CXCL13 siRNA (Human) - CRH7184 from Cohesion Biosciences
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CXCL13/BLC/BCA-1 RNAi - H00010563-R01 from Novus Biologicals
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CXCL13 - MBS8223795 from MyBioSource
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shRNA set against Human CXCL13 (NM_006419.2) - SHH272153 from Creative biogene
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Human CXCL13 siRNA - orb267686 from Biorbyt
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CXCL13 shRNA Plasmid (Human) - CHH7184 from Cohesion Biosciences
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CXCL13 miRNA 3'UTR clone - MiUTR3H-07413 from Creative biogene
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