| Gene Symbol |
MPO
|
| Entrez Gene |
4353
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
myeloperoxidase
|
| Other Description |
-
|
| Swissprots |
A1L4B8 Q9UCL7 Q4PJH5 P05164 Q14862
|
| Accessions |
AAA59864 AAA59865 AAA60346 AAY68218 BAA03362 CAA00809 CAA33438 CAA45918 CAA85783 CAS01769 CAS01770 EAW94470 EAW94471 EAW94472 EAW94473 P05164 BC130476 AAI30477 HQ258645 ADR83396 J02694 AAA59896 M19507 AAA59863 S56200 AAB25582 X04876 CAA28564 XM_011524821 XP_011523123 XM_011524822 XP_011523124 XM_011524823 XP_011523125 NM_000250 NP_000241
|
| Function |
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
|
| Subcellular Location |
Lysosome.
|
| Top Pathways |
Phagosome, Transcriptional misregulation in cancer
|
