Gene Symbol | HRAS |
---|---|
Entrez Gene | 3265 |
Alt Symbol | C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21ras |
Species | Human |
Gene Type | protein-coding |
Description | Harvey rat sarcoma viral oncogene homolog |
Other Description | GTP- and GDP-binding peptide B|GTPase HRas|Ha-Ras1 proto-oncoprotein|Harvey rat sarcoma viral oncoprotein|Ras family small GTP binding protein H-Ras|c-has/bas p21 protein|c-ras-Ki-2 activated oncogene|p19 H-RasIDX protein|transformation gene: oncogene HAMSV|transforming protein p21|v-Ha-ras Harvey rat sarcoma viral oncogene homolog |
Swissprots | Q6FHV9 B5BUA0 Q9UCE2 Q14080 Q9BR65 P01112 |
Accessions | AAA35683 AAA35685 AAA35687 AAA36557 AAA52693 AAB02605 AAK56963 ABI97389 CAA25624 CAA34461 CAN37622 CBV35641 CDL93477 EAX02337 EAX02338 EAX02339 EAX02340 EAX02341 P01112 AB451336 BAG70150 AB451485 BAG70299 AF493916 AAM12630 AJ437024 CAD24594 BC006499 AAH06499 BC095471 AAH95471 BM801632 BQ574535 BQ674260 BT019421 AAV38228 CR536579 CAG38816 CR542271 CAG47067 DN990077 KJ534867 AHW56507 KJ534868 AHW56508 XR_242795 XR_430702 NM_001130442 NP_001123914 NM_005343 NP_005334 NM_176795 NP_789765 |
Function | Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. {ECO:0000269|PubMed:12740440, ECO:0000269|PubMed:14500341, ECO:0000269|PubMed:9020151}. |
Subcellular Location | Cell membrane. Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus. Golgi apparatus membrane; Lipid-anchor. Note=The active GTP-bound form is localized most strongly to membranes than the inactive GDP-bound form (By similarity). Shuttles between the plasma membrane and the Golgi apparatus. {ECO:0000250}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:14500341}. |
Top Pathways | Central carbon metabolism in cancer, Axon guidance, Viral carcinogenesis, Estrogen signaling pathway, Sphingolipid signaling pathway |
Active H-Ras (G12V) full length protein - ab90627 from Abcam
|
||||||||||
Active human GTPase HRAS protein fragment - ab90766 from Abcam
|
||||||||||
Active human H-Ras (G12V) (mutated G12 V) full length protein - ab140571 from Abcam
|
||||||||||
GTPase HRAS peptide - ab107789 from Abcam
|
||||||||||
Human GTPase HRAS (mutated G12 V) full length protein - ab90205 from Abcam
|
||||||||||
Human GTPase HRAS (mutated Q61 L) full length protein - ab90742 from Abcam
|
||||||||||
Human GTPase HRAS (mutated S17 N) full length protein - ab90767 from Abcam
|
||||||||||
Human GTPase HRAS full length protein - ab93949 from Abcam
|
||||||||||
Human GTPase HRAS full length protein - ab176670 from Abcam
|
||||||||||
Human HRAS full length protein - ab193742 from Abcam
|
||||||||||
Human Ras full length protein - ab176621 from Abcam
|
||||||||||
Human Ras full length protein - ab61239 from Abcam
|
||||||||||
HRAS / H-Ras Antibody Blocking Peptide - LS-E1145 from LifeSpan Bioscience
|
||||||||||
HRAS / H-Ras Antibody Blocking Peptide - LS-E6720 from LifeSpan Bioscience
|
||||||||||
HRAS / H-Ras Antibody Blocking Peptide - LS-E9246 from LifeSpan Bioscience
|
||||||||||
Recombinant Human vH RAS Protein - NBP1-50831 from Novus Biologicals
|
||||||||||
vH RAS Partial Recombinant Protein - H00003265-Q01 from Novus Biologicals
|
||||||||||
vH RAS Recombinant Protein - H00003265-P01 from Novus Biologicals
|
||||||||||
HRAS-Antibody-C-term-Blocking-peptide - BP11676b from Abgent, a WuXi AppTec company
|
||||||||||
HRAS-Antibody-Center-Blocking-Peptide - BP7764c from Abgent, a WuXi AppTec company
|
||||||||||
Recombinant rat GTPase HRas protein (OPCA01077) - OPCA01077 from Aviva Systems Biology
|
||||||||||
HRAS Protein (OPPA02394) - OPPA02394 from Aviva Systems Biology
|
||||||||||
Human V-Ha-ras Harvey Rat Sarcoma Viral Oncogene Homolog protein - orb81167 from Biorbyt
|
||||||||||
Human HRAS His tag protein - orb84548 from Biorbyt
|
||||||||||
GTPase HRas protein (His tag) - 80R-3404 from Fitzgerald
|