Gene Symbol | PLAU |
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Entrez Gene | 5328 |
Alt Symbol | ATF, BDPLT5, QPD, UPA, URK, u-PA |
Species | Human |
Gene Type | protein-coding |
Description | plasminogen activator, urokinase |
Other Description | U-plasminogen activator|plasminogen activator, urinary|urokinase-type plasminogen activator |
Swissprots | Q53XS3 Q16618 Q15844 Q5SWW9 B4DPZ2 P00749 Q969W6 |
Accessions | AAA61252 AAA61257 AAK53822 CAA01559 CAA26268 CAJ18774 CBX47479 EAW54544 EAW54545 P00749 A18397 CAA01390 A35395 CAA02215 AB208961 BAD92198 AK297940 BAG60256 AK298560 BAG60754 AK312960 BAG35799 AW316981 AY029537 AAK38734 AY820134 AAV70488 BC013575 AAH13575 BI759308 BI833559 BQ920793 BT007391 AAP36055 BX360462 CB959931 D00244 BAA00175 D11143 BAA01919 DC349055 DQ893817 ABM84743 K03226 AAC97138 M15476 AAA61253 X02760 CAA26535 Z36790 XM_011539866 XP_011538168 XM_011539867 XP_011538169 NM_001145031 NP_001138503 NM_002658 NP_002649 |
Function | Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed in the prostate gland and prostate cancers. {ECO:0000269|PubMed:15988036}. |
Top Pathways | Complement and coagulation cascades, MicroRNAs in cancer, Proteoglycans in cancer, Transcriptional misregulation in cancer |
Active dog Urokinase full length protein - ab92592 from Abcam
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Active human uPA full length protein - ab167714 from Abcam
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Active human Urokinase full length protein - ab92737 from Abcam
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Active mouse Urokinase full length protein - ab92641 from Abcam
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Active mouse Urokinase full length protein - ab92644 from Abcam
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Active rabbit Urokinase full length protein - ab92603 from Abcam
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Active rat Urokinase full length protein - ab92604 from Abcam
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Human PAI1 + PLAU full length protein - ab92553 from Abcam
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Human Urokinase full length protein - ab151834 from Abcam
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Human Urokinase full length protein - ab92767 from Abcam
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Human Urokinase full length protein - ab93152 from Abcam
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Human Urokinase full length protein - ab51966 from Abcam
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Human Urokinase full length protein - ab96627 from Abcam
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Human Urokinase full length protein - ab96628 from Abcam
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Human Urokinase protein fragment - ab159135 from Abcam
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Human Urokinase protein fragment - ab95235 from Abcam
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Human Urokinase protein fragment - ab92591 from Abcam
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Mouse Urokinase full length protein - ab92645 from Abcam
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Mouse Urokinase full length protein - ab92642 from Abcam
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Mouse Urokinase protein fragment - ab92598 from Abcam
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Urokinase peptide (414-427) - ab45809 from Abcam
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PLAU / Urokinase / uPA Antibody Blocking Peptide - LS-E25945 from LifeSpan Bioscience
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PLAU / Urokinase / uPA Antibody Blocking Peptide - LS-E23246 from LifeSpan Bioscience
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PLAU / Urokinase / uPA Antibody Blocking Peptide - LS-E9549 from LifeSpan Bioscience
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u-Plasminogen Activator/Urokinase Partial Recombinant Protein - H00005328-Q01 from Novus Biologicals
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