| Gene Symbol | ATP6V1C1 |
|---|---|
| Entrez Gene | 528 |
| Alt Symbol | ATP6C, ATP6D, VATC, Vma5 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| Other Description | H(+)-transporting two-sector ATPase, subunit C|H+ -ATPase C subunit|H+-transporting ATPase chain C, vacuolar|V-ATPase C subunit|V-ATPase subunit C 1|V-type proton ATPase subunit C 1|subunit C of vacuolar proton-ATPase V1 domain|vacuolar ATP synthase subunit C|vacuolar proton pump C subunit|vacuolar proton pump subunit C 1|vacuolar proton pump, 42-kD subunit|vacuolar proton-ATPase, subunit C, VI domain |
| Swissprots | P21283 |
| Accessions | AAL50383 CAD33297 EAW91859 EAW91860 P21283 AA242944 AK000064 AK090702 AK298617 BAH12829 AK308632 AL707882 AU137773 AV649881 AW505309 BC010960 AAH10960 BI821321 BX648079 EU832346 ACE87603 EU832431 ACE86916 HQ447211 ADQ31698 J05682 AAA36803 X69151 CAA48903 NM_001695 NP_001686 NM_001007254 |
| Function | Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:12384298}. |
| Top Pathways | Epithelial cell signaling in Helicobacter pylori infection, Vibrio cholerae infection, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis |