| Gene Symbol |
ATP6V1C1
|
| Entrez Gene |
528
|
| Alt Symbol |
ATP6C, ATP6D, VATC, Vma5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
|
| Other Description |
H(+)-transporting two-sector ATPase, subunit C|H+ -ATPase C subunit|H+-transporting ATPase chain C, vacuolar|V-ATPase C subunit|V-ATPase subunit C 1|V-type proton ATPase subunit C 1|subunit C of vacuolar proton-ATPase V1 domain|vacuolar ATP synthase subunit C|vacuolar proton pump C subunit|vacuolar proton pump subunit C 1|vacuolar proton pump, 42-kD subunit|vacuolar proton-ATPase, subunit C, VI domain
|
| Swissprots |
P21283
|
| Accessions |
AAL50383 CAD33297 EAW91859 EAW91860 P21283 AA242944 AK000064 AK090702 AK298617 BAH12829 AK308632 AL707882 AU137773 AV649881 AW505309 BC010960 AAH10960 BI821321 BX648079 EU832346 ACE87603 EU832431 ACE86916 HQ447211 ADQ31698 J05682 AAA36803 X69151 CAA48903 NM_001695 NP_001686 NM_001007254
|
| Function |
Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:12384298}.
|
| Top Pathways |
Epithelial cell signaling in Helicobacter pylori infection, Vibrio cholerae infection, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis
|
![Western Blot: ATP6V1C1 Overexpression Lysate (Adult Normal) [NBL1-07840] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ATP6V1C1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/10781_ATP6V1C1%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-07840-img0002.jpg)