Gene Symbol | ATP6V1C1 |
---|---|
Entrez Gene | 528 |
Alt Symbol | ATP6C, ATP6D, VATC, Vma5 |
Species | Human |
Gene Type | protein-coding |
Description | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
Other Description | H(+)-transporting two-sector ATPase, subunit C|H+ -ATPase C subunit|H+-transporting ATPase chain C, vacuolar|V-ATPase C subunit|V-ATPase subunit C 1|V-type proton ATPase subunit C 1|subunit C of vacuolar proton-ATPase V1 domain|vacuolar ATP synthase subunit C|vacuolar proton pump C subunit|vacuolar proton pump subunit C 1|vacuolar proton pump, 42-kD subunit|vacuolar proton-ATPase, subunit C, VI domain |
Swissprots | P21283 |
Accessions | AAL50383 CAD33297 EAW91859 EAW91860 P21283 AA242944 AK000064 AK090702 AK298617 BAH12829 AK308632 AL707882 AU137773 AV649881 AW505309 BC010960 AAH10960 BI821321 BX648079 EU832346 ACE87603 EU832431 ACE86916 HQ447211 ADQ31698 J05682 AAA36803 X69151 CAA48903 NM_001695 NP_001686 NM_001007254 |
Function | Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:12384298}. |
Top Pathways | Epithelial cell signaling in Helicobacter pylori infection, Vibrio cholerae infection, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis |
V-ATPase C1 CRISPR/Cas9 KO Plasmid (h) - sc-402679 from Santa Cruz Biotechnology
|
||||||||
V-ATPase C1 HDR Plasmid (h) - sc-402679-HDR from Santa Cruz Biotechnology
|
||||||||
V-ATPase C1 Double Nickase Plasmid (h) - sc-402679-NIC from Santa Cruz Biotechnology
|
||||||||
V-ATPase C1 Double Nickase Plasmid (h2) - sc-402679-NIC-2 from Santa Cruz Biotechnology
|
||||||||
V-ATPase C1 CRISPR Activation Plasmid (h) - sc-402679-ACT from Santa Cruz Biotechnology
|
||||||||
V-ATPase C1 CRISPR Activation Plasmid (h2) - sc-402679-ACT-2 from Santa Cruz Biotechnology
|
||||||||
V-ATPase C1 Lentiviral Activation Particles (h) - sc-402679-LAC from Santa Cruz Biotechnology
|
||||||||
V-ATPase C1 Lentiviral Activation Particles (h2) - sc-402679-LAC-2 from Santa Cruz Biotechnology
|
||||||||
V-ATPase C1 siRNA (h) - sc-36789 from Santa Cruz Biotechnology
|
||||||||
V-ATPase C1 shRNA Plasmid (h) - sc-36789-SH from Santa Cruz Biotechnology
|
||||||||
V-ATPase C1 shRNA (h) Lentiviral Particles - sc-36789-V from Santa Cruz Biotechnology
|
||||||||
ATP6V1C1 RNAi - H00000528-R04 from Novus Biologicals
|
||||||||
ATP6V1C1 RNAi - H00000528-R03 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU027501 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN3729 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3729 from Sigma-Aldrich
|
||||||||
ATP6V1C1 siRNA (Human) - CRH0366 from Cohesion Biosciences
|
||||||||
ATP6V1C1 - MBS8218180 from MyBioSource
|
||||||||
shRNA set against Human ATP6V1C1 (NM_001695.4) - SHH243130 from Creative biogene
|
||||||||
shRNA set against Human ATP6V1C1(NM_001695.4) - SHG083797 from Creative biogene
|
||||||||
Human ATP6V1C1 siRNA - orb260868 from Biorbyt
|
||||||||
ATP6V1C1 shRNA Plasmid (Human) - CHH0366 from Cohesion Biosciences
|
||||||||
ATP6V1C1 miRNA 3'UTR clone - MiUTR1H-00717 from Creative biogene
|