| Gene Symbol |
NDUFS5
|
| Entrez Gene |
4725
|
| Alt Symbol |
CI-15k, CI15K
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)
|
| Other Description |
CI-15 kDa|NADH dehydrogenase [ubiquinone] iron-sulfur protein 5|NADH:ubiquinone oxidoreductase 15 kDa IP subunit|complex I-15 kDa
|
| Swissprots |
O43920
|
| Accessions |
EAX07286 EAX07287 O43920 AF020352 AAB87866 AF047434 AAC39878 AF086268 AI244607 AK312188 BAG35121 BC001884 AAH01884 BC093057 AAH93057 CR456904 CAG33185 JF432447 ADZ15664 NM_001184979 NP_001171908 NM_004552 NP_004543
|
| Function |
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
|
| Subcellular Location |
Mitochondrion. Mitochondrion inner membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Mitochondrion intermembrane space {ECO:0000305}.
|
| Top Pathways |
Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation
|