Gene Symbol | NDUFS5 |
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Entrez Gene | 4725 |
Alt Symbol | CI-15k, CI15K |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) |
Other Description | CI-15 kDa|NADH dehydrogenase [ubiquinone] iron-sulfur protein 5|NADH:ubiquinone oxidoreductase 15 kDa IP subunit|complex I-15 kDa |
Swissprots | O43920 |
Accessions | EAX07286 EAX07287 O43920 AF020352 AAB87866 AF047434 AAC39878 AF086268 AI244607 AK312188 BAG35121 BC001884 AAH01884 BC093057 AAH93057 CR456904 CAG33185 JF432447 ADZ15664 NM_001184979 NP_001171908 NM_004552 NP_004543 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Subcellular Location | Mitochondrion. Mitochondrion inner membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Mitochondrion intermembrane space {ECO:0000305}. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFS5 CRISPR/Cas9 KO Plasmid (h) - sc-417982 from Santa Cruz Biotechnology
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NDUFS5 HDR Plasmid (h) - sc-417982-HDR from Santa Cruz Biotechnology
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NDUFS5 Double Nickase Plasmid (h) - sc-417982-NIC from Santa Cruz Biotechnology
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NDUFS5 Double Nickase Plasmid (h2) - sc-417982-NIC-2 from Santa Cruz Biotechnology
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NDUFS5 CRISPR Activation Plasmid (h) - sc-417982-ACT from Santa Cruz Biotechnology
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NDUFS5 CRISPR Activation Plasmid (h2) - sc-417982-ACT-2 from Santa Cruz Biotechnology
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NDUFS5 Lentiviral Activation Particles (h) - sc-417982-LAC from Santa Cruz Biotechnology
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NDUFS5 Lentiviral Activation Particles (h2) - sc-417982-LAC-2 from Santa Cruz Biotechnology
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NDUFS5 siRNA (h) - sc-88473 from Santa Cruz Biotechnology
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NDUFS5 shRNA Plasmid (h) - sc-88473-SH from Santa Cruz Biotechnology
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NDUFS5 shRNA (h) Lentiviral Particles - sc-88473-V from Santa Cruz Biotechnology
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NDUFS5 RNAi - H00004725-R01 from Novus Biologicals
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MISSION® esiRNA - EHU057031 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15170 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15170 from Sigma-Aldrich
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NDUFS5 siRNA (Human) - CRH3138 from Cohesion Biosciences
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NDUFS5 shRNA Plasmid (Human) - CHH3138 from Cohesion Biosciences
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