Gene Symbol | HDAC9 |
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Entrez Gene | 9734 |
Alt Symbol | HD7, HD7b, HD9, HDAC, HDAC7, HDAC7B, HDAC9B, HDAC9FL, HDRP, MITR |
Species | Human |
Gene Type | protein-coding |
Description | histone deacetylase 9 |
Other Description | MEF-2 interacting transcription repressor (MITR) protein|histone deacetylase 4/5-related protein|histone deacetylase 7B |
Swissprots | O94845 Q2M2R6 Q9UKV0 Q86SL1 A7E2F3 E7EX34 B7Z4I4 Q86US3 O95028 C9JS87 B7Z928 F8W9E0 B7Z917 B7Z940 |
Accessions | AAC78618 AAD15364 AAS07401 AAS07402 AAS07409 AAS07422 AAS07423 AAS07424 EAW93701 EAW93702 EAW93703 EAW93704 EAW93705 EAW93706 EAW93707 EAW93708 EAW93709 EAW93710 Q9UKV0 AA405905 AB018287 BAA34464 AF124924 AAF04254 AJ459808 CAD30851 AK095820 BAC04630 AK097178 BAC04971 AK296214 BAH12283 AK297404 BAH12570 AK304298 BAH14153 AK304343 BAH14164 AK304410 BAH14176 AK316109 BAH14480 AY032737 AAK66821 AY032738 AAK66822 AY197371 AAO27363 AY429540 BC092441 BC111735 AAI11736 BC150328 AAI50329 BC152405 AAI52406 CR749550 CAH18349 DC369193 EU832154 ACE87504 EU832247 ACE86817 EU832248 ACE86818 XM_011515626 XP_011513928 XM_011515627 XP_011513929 XM_011515628 XP_011513930 XM_011515629 XP_011513931 XM_011515630 XP_011513932 XM_011515631 XP_011513933 XM_011515632 XP_011513934 XM_011515633 XP_011513935 XM_011515634 XP_011513936 XM_011515635 XP_011513937 XM_011515636 XP_011513938 XM_011515637 XP_011513939 XM_011515638 XP_011513940 XM_011515639 XP_011513941 XM_011515640 XP_011513942 XM_011515641 XP_011513943 XM_011515642 XP_011513944 XM_011515643 XP_011513945 XM_011515644 XP_011513946 XM_011515645 XP_011513947 XM_011515646 XP_011513948 XM_011515647 XP_011513949 XM_011515648 XP_011513950 XM_011515649 XP_011513951 XM_011515650 XP_011513952 XM_011515651 XP_011513953 XR_926952 NM_001204144 NP_001191073 NM_001204145 NP_001191074 NM_001204146 NP_001191075 NM_001204147 NP_001191076 NM_001204148 NP_001191077 NM_014707 NP_055522 NM_058176 NP_478056 NM_178423 NP_848510 NM_178425 NP_848512 NM_058177 |
Function | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription. |
Subcellular Location | Nucleus {ECO:0000250}. |
Tissue Specificity | Broadly expressed, with highest levels in brain, heart, muscle and testis. Isoform 3 is present in human bladder carcinoma cells (at protein level). {ECO:0000269|PubMed:10655483, ECO:0000269|PubMed:11535832, ECO:0000269|PubMed:12590135, ECO:0000269|PubMed:12706107}. |
Top Pathways | Viral carcinogenesis, Alcoholism |
Active human HDAC9 protein fragment - ab80350 from Abcam
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HDAC9 peptide - ab41711 from Abcam
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HDAC9 peptide - ab124130 from Abcam
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Human HDAC9 peptide - ab104383 from Abcam
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HDAC7 Antibody Blocking Peptide - LS-E2588 from LifeSpan Bioscience
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HDAC7 Antibody Blocking Peptide - LS-E13358 from LifeSpan Bioscience
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HDAC9 Antibody Blocking Peptide - LS-E741 from LifeSpan Bioscience
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HDAC9 Antibody Blocking Peptide - LS-E742 from LifeSpan Bioscience
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HDAC9 Antibody Blocking Peptide - LS-E15748 from LifeSpan Bioscience
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HDAC9 Recombinant Protein - H00009734-P01 from Novus Biologicals
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Recombinant Human HDAC7 Protein - H00051564-P01 from Novus Biologicals
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Recombinant Human HDAC9 Protein - H00009734-Q01 from Novus Biologicals
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HDAC9 Peptide - P0225 from Novus Biologicals
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HDAC9 Peptide - P0224 from Novus Biologicals
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HDAC7 Peptide - P0220 from Novus Biologicals
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HDAC9-Antibody-C-term-Blocking-Peptide - BP1109b from Abgent, a WuXi AppTec company
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HDAC9-Antibody-N-term-Blocking-Peptide - BP1109a from Abgent, a WuXi AppTec company
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Recombinant human Histone deacetylase 9 (OPCA01151) - OPCA01151 from Aviva Systems Biology
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HDAC 7 Blocking Peptide - 33R-10522 from Fitzgerald
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HDAC 9 Blocking Peptide - 33R-10524 from Fitzgerald
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HDAC7 Blocking Peptide - 33R-10832 from Fitzgerald
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HDAC9 Blocking Peptide - 33R-7773 from Fitzgerald
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HDAC9 Blocking Peptide - 33R-10834 from Fitzgerald
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HDAC9 Blocking Peptide - 33R-3517 from Fitzgerald
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Histone Deacetylase 9 Blocking Peptide - abx063613 from Abbexa
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