HDAC9

Gene Symbol HDAC9
Entrez Gene 9734
Alt Symbol HD7, HD7b, HD9, HDAC, HDAC7, HDAC7B, HDAC9B, HDAC9FL, HDRP, MITR
Species Human
Gene Type protein-coding
Description histone deacetylase 9
Other Description MEF-2 interacting transcription repressor (MITR) protein|histone deacetylase 4/5-related protein|histone deacetylase 7B
Swissprots O94845 Q2M2R6 Q9UKV0 Q86SL1 A7E2F3 E7EX34 B7Z4I4 Q86US3 O95028 C9JS87 B7Z928 F8W9E0 B7Z917 B7Z940
Accessions AAC78618 AAD15364 AAS07401 AAS07402 AAS07409 AAS07422 AAS07423 AAS07424 EAW93701 EAW93702 EAW93703 EAW93704 EAW93705 EAW93706 EAW93707 EAW93708 EAW93709 EAW93710 Q9UKV0 AA405905 AB018287 BAA34464 AF124924 AAF04254 AJ459808 CAD30851 AK095820 BAC04630 AK097178 BAC04971 AK296214 BAH12283 AK297404 BAH12570 AK304298 BAH14153 AK304343 BAH14164 AK304410 BAH14176 AK316109 BAH14480 AY032737 AAK66821 AY032738 AAK66822 AY197371 AAO27363 AY429540 BC092441 BC111735 AAI11736 BC150328 AAI50329 BC152405 AAI52406 CR749550 CAH18349 DC369193 EU832154 ACE87504 EU832247 ACE86817 EU832248 ACE86818 XM_011515626 XP_011513928 XM_011515627 XP_011513929 XM_011515628 XP_011513930 XM_011515629 XP_011513931 XM_011515630 XP_011513932 XM_011515631 XP_011513933 XM_011515632 XP_011513934 XM_011515633 XP_011513935 XM_011515634 XP_011513936 XM_011515635 XP_011513937 XM_011515636 XP_011513938 XM_011515637 XP_011513939 XM_011515638 XP_011513940 XM_011515639 XP_011513941 XM_011515640 XP_011513942 XM_011515641 XP_011513943 XM_011515642 XP_011513944 XM_011515643 XP_011513945 XM_011515644 XP_011513946 XM_011515645 XP_011513947 XM_011515646 XP_011513948 XM_011515647 XP_011513949 XM_011515648 XP_011513950 XM_011515649 XP_011513951 XM_011515650 XP_011513952 XM_011515651 XP_011513953 XR_926952 NM_001204144 NP_001191073 NM_001204145 NP_001191074 NM_001204146 NP_001191075 NM_001204147 NP_001191076 NM_001204148 NP_001191077 NM_014707 NP_055522 NM_058176 NP_478056 NM_178423 NP_848510 NM_178425 NP_848512 NM_058177
Function Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription.
Subcellular Location Nucleus {ECO:0000250}.
Tissue Specificity Broadly expressed, with highest levels in brain, heart, muscle and testis. Isoform 3 is present in human bladder carcinoma cells (at protein level). {ECO:0000269|PubMed:10655483, ECO:0000269|PubMed:11535832, ECO:0000269|PubMed:12590135, ECO:0000269|PubMed:12706107}.
Top Pathways Viral carcinogenesis, Alcoholism

HDAC9 (B-1) - sc-398003 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HDAC9 (B-1): sc-398003. Western blot analysis of HDAC9 expression in Ramos whole cell lysate.

HDAC9 (H-45) - sc-28732 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
HDAC9 (H-45): sc-28732. Western blot analysis of HDAC9 expression in Ramos nuclear extract.

HDAC9 (G-15) - sc-10408 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HDAC9 (G-15): sc-10408. Western blot analysis of HDAC9 expression in non-transfected 293T: sc-117752 (A) and human HDAC9 transfected 293T: sc-177328 (B) whole cell lysates.

HDAC9 (N-20) - sc-32094 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HDAC9 (N-20): sc-32094. Western blot analysis of HDAC9 expression in Ramos whole cell lysate.

HDAC9 (P-17) - sc-32095 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HDAC9 (P-17): sc-32095. Western blot analysis of HDAC9 expression in non-transfected 293T: sc-117752 (A) and human HDAC9 transfected 293T: sc-177328 (B) whole cell lysates.

HDAC9 (V-16) - sc-30744 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

p-HDAC4/5/9 (Ser 246/259/220) - sc-135656 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
p-HDAC4/5/9 (Ser 246/259/220): sc-135656. Western blot analysis of phosphorylated HDAC4/5/9 expression in untreated (A) and Insulin-treated (B) 3T3 cell extracts.

Anti-HDAC9 antibody - ab18970 from Abcam

Prices $400.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-HDAC9 antibody (ab18970) at 2.5 µg/ml + mouse intestine tissue lysate 50ugObserved band size : 110-140 kDa (why is the actual band size different from the predicted?)Additional bands at : 60 kDa,75 kDa. We are unsure as to the identity of these extra bands.

Anti-HDAC9 antibody - ab53102 from Abcam

Prices $379.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab53102 stained HepG2 cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab53102 at 5µg/ml overnight at +4°C. The secondary antibody (pseudo-colored green) was Dylight® 488 goat anti- rabbit (ab96899) IgG (H+L) preadsorbed, used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (pseudo-colored red) at a 1/200 dilution for 1h at room temperature. DAPI was used to stain the cell nuclei (pseudo-colored blue) at a concentration of 1.43µM for 1hour at room temperature.

Anti-HDAC9 antibody - ab70954 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HDAC9 antibody (ab70954) at 1/100 dilutionLane 1 : Non-transfected Hela cellsLane 2 : HDAC9 transfected Hela cells

Anti-HDAC9 antibody - ab86140 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HDAC9 antibody (ab86140) at 1 µg/mlLane 1 : Testis (Human) Tissue Lysate - adult normal tissue (ab30257)Lane 2 : MCF7 (Human breast adenocarcinoma cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-HDAC9 antibody [EPR5223] - ab109446 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5223
All lanes : Anti-HDAC9 antibody [EPR5223] (ab109446) at 1/10000 dilutionLane 1 : K562 cell lysateLane 2 : HepG2 cell lysateLane 3 : Raji cell lysateLysates/proteins at 10 µg per lane.

Anti-HDAC9 antibody - C-terminal - ab135083 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-HDAC9 antibody - C-terminal (ab135083) at 1/1000 dilution + Mouse brain total cell extract

Anti-HDAC9 antibody - ChIP Grade - ab59718 from Abcam

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ChIP analysis using ab59718 (0.5µg/mL) binding HDAC9 in human HCT116 colon cancer cells. Without (- peptide) and with (+ peptide) blocking peptide. Protein binding was detected using real-time PCR.

Anti-HDAC7 Antibody (aa846-875, Azide-free, HRP) - LS-C249172 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HDAC7 Antibody - LS-C285782 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HDAC7 Antibody (aa883-932) - LS-C292048 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HDAC7 Antibody (aa100-149) - LS-C292050 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HDAC7 Antibody (clone 2B11-1C1) - LS-C308196 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2B11-1C1

Anti-HDAC7 Antibody - LS-C310586 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HDAC7 Antibody (aa846-875) - LS-C166824 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
HDAC7 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human stomach tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-HDAC7 Antibody (Gly932) - LS-C176061 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of HDAC7 (G932) pAb in paraffin-embedded human lung carcinoma tissue.

Anti-HDAC7 Antibody (Biotin) - LS-C316662 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HDAC7 Antibody - LS-C310587 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HDAC7 Antibody (FITC) - LS-C316663 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Search more