| Gene Symbol |
CYP11B1
|
| Entrez Gene |
1584
|
| Alt Symbol |
CPN1, CYP11B, FHI, P450C11
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cytochrome P450, family 11, subfamily B, polypeptide 1
|
| Other Description |
CYPXIB1|cytochrome P-450c11|cytochrome P450 11B1, mitochondrial|cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 1|cytochrome P450C11|cytochrome p450 XIB1|steroid 11-beta-hydroxylase|steroid 11-beta-monooxygenase
|
| Swissprots |
P15538 Q4VAQ9 Q14095 Q9UML2 Q4VAQ8
|
| Accessions |
AAA52149 ABX82059 ABY87528 ACZ81439 BAA01039 BAA03717 BAB71992 CAD24087 CAD24088 CAD24089 CAD24090 EAW82293 EAW82294 EAW82295 P15538 AF478474 AAL84813 AK094090 BAC04283 BC096285 AAH96285 BC096286 AAH96286 BC096287 AAH96287 BX647738 M24667 AAA52148 X55764 CAA39290 XM_011516870 XP_011515172 XM_011516871 XP_011515173 XM_011516872 XP_011515174 XM_011516873 XP_011515175 XM_011516874 XP_011515176 XM_011516875 XP_011515177 XM_011516876 XP_011515178 NM_000497 NP_000488 NM_001026213 NP_001021384
|
| Function |
Has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB.
|
| Subcellular Location |
Mitochondrion membrane.
|
| Top Pathways |
Steroid hormone biosynthesis
|
![Western Blot: CYP11B1 Overexpression Lysate (Adult Normal) [NBP2-04159] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CYP11B1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8723_CYP11B1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04159-img0001.jpg)