CYP11B1

Gene Symbol CYP11B1
Entrez Gene 1584
Alt Symbol CPN1, CYP11B, FHI, P450C11
Species Human
Gene Type protein-coding
Description cytochrome P450, family 11, subfamily B, polypeptide 1
Other Description CYPXIB1|cytochrome P-450c11|cytochrome P450 11B1, mitochondrial|cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 1|cytochrome P450C11|cytochrome p450 XIB1|steroid 11-beta-hydroxylase|steroid 11-beta-monooxygenase
Swissprots P15538 Q4VAQ9 Q14095 Q9UML2 Q4VAQ8
Accessions AAA52149 ABX82059 ABY87528 ACZ81439 BAA01039 BAA03717 BAB71992 CAD24087 CAD24088 CAD24089 CAD24090 EAW82293 EAW82294 EAW82295 P15538 AF478474 AAL84813 AK094090 BAC04283 BC096285 AAH96285 BC096286 AAH96286 BC096287 AAH96287 BX647738 M24667 AAA52148 X55764 CAA39290 XM_011516870 XP_011515172 XM_011516871 XP_011515173 XM_011516872 XP_011515174 XM_011516873 XP_011515175 XM_011516874 XP_011515176 XM_011516875 XP_011515177 XM_011516876 XP_011515178 NM_000497 NP_000488 NM_001026213 NP_001021384
Function Has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB.
Subcellular Location Mitochondrion membrane.
Top Pathways Steroid hormone biosynthesis

CYP11B (D-18) - sc-32372 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CYP11B1 (H-11) - sc-374096 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP11B (H-11): sc-374096. Western blot analysis of CYP11B expression in MCF7 (A) and Caki-1 (B) whole cell lysates.

CYP11B1 (G-14) - sc-47647 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CYP11B1 (N-12) - sc-47649 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CYP11B1 (N-12): sc-47649. Western blot analysis of CYP11B1 expression in Caki-1 whole cell lysate.

CYP11B1/2 (N-300) - sc-135198 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-CYP11B1 + CYP11B2 antibody - N-terminal - ab190557 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CYP11B1 + CYP11B2 antibody - N-terminal (ab190557) at 1/500 dilution + HT29 cell extract at 30 µg

Anti-CYP11B1 antibody - ab197908 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue labeling CYP11B1 with ab197908 at 1/25 dilution.

Anti-CYP11B1 antibody - ab71561 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CYP11B1 antibody - ab171888 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CYP11B1 antibody (ab171888) at 1 µg/mlLane 1 : CYP11B1 transfected 293T cell lysateLane 2 : Non- transfected 293T cell lysateSecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-CYP11B1 antibody - ab77938 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-CYP11B1 Antibody - LS-C310061 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP11B1 Antibody (aa202-251) - LS-C135724 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CYP11B1 antibody LS-C135724 Western blot of HeLa lysate.

Anti-CYP11B1 Antibody (aa331-380) - LS-C135723 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CYP11B1 antibody LS-C135723 Western blot of Fetal Liver lysate.

Anti-CYP11B1 Antibody (aa436-450) - LS-C312848 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
WB of CYP11B1 antibody. Lane 1: HELA Cell Lysate. Lane 2: U87 Cell Lysate. Lane 3: M231 Cell Lysate. Lane 4: PANC Cell Lysate. Lane 5: M453 Cell Lysate. Lane 6: HELA Cell Lysate. Lane 7: SMMC Cell Lysate.

CPN1 Antibody - NBP1-85851 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Western Blot: CPN1 Antibody [NBP1-85851] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp<br/>Lane 4: Human plasma (IgG/HSA depleted)

CYP11B1 Antibody - NBP1-68883 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CYP11B1 Antibody [NBP1-68883] - 1. HEK293TN-GFP-hcyp11B1 (75ug) 2. HEK293TN-GFP-hcyp11B2 (75ug) Primary dilution: 1 : 100 Secondary Antibody: mouse anti-Rabbit HRP Secondary Dilution: 1 : 10,000Film Exposed for: 5 minutesImage Submitted by: Celso Gomez-SanchezMongomery VA Medical Center.

CYP11B1 Antibody - NBP1-68882 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

CPN1 Antibody - NBP1-00764 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: CPN1 Antibody [NBP1-00764] - Western blot (WB) analysis of CPN1 cat (Q452) antibody in extracts from RAW264.7 cell

CYP11B1 Antibody - H00001584-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

CYP11B1 Antibody - H00001584-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: CYP11B1 Antibody [H00001584-B01] - analysis of CYP11B1 expression in transfected 293T cell line by CYP11B1 MaxPab polyclonal antibody (B01). Lane 1: CYP11B1 transfected lysate (65.10 KDa). Lane 2: Non-transfected lysate.

CYP11B1 Polyclonal Antibody - bs-3898R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
L1 rat kidney, L2 rat brain lysates probed (bs-3898R) at 1:200 in 4˚C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 90min in 37˚C. Predicted band and observed band size: 55kDa

Anti-CYP11B1 antibody produced in rabbit - SAB1401106 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-CYP11B1, antibody produced in rabbit, purified immunoglobulin: <B>Cat. No. SAB1401106</B>: Antibody concentration: 0.1 - 5.0 μg/mL. Specific band of ~65.10 kDa using CYP11B1 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-CYP11B1 antibody produced in rabbit - SAB2107499 from Sigma-Aldrich

Prices $341.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CYP11B1: <B>Cat. No. SAB2107499</B>: Western blot analysis of CYP11B1 with CYP11B1 (cytochrome P450, family 11, subfamily B, polypeptide 1) antibody against the C terminal of CYP11B1 (50 μg) antibody at 1.0 μg/mL.

Anti-CYP11B1 antibody produced in rabbit - SAB2107500 from Sigma-Aldrich

Prices $341.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CYP11B1: <B>Cat. No. SAB2107500</B>: Western blot analysis of CYP11B1 with CYP11B1 (cytochrome P450, family 11, subfamily B, polypeptide 1) antibody against the middle region of CYP11B1 (50 μg) antibody at 1.0 μg/mL.

CYP11B1 antibody - C-terminal region (ARP60140_P050) - ARP60140_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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